Post-Transcriptional Light Regulation of Nuclear-Encoded Genes

Petracek, Marie E.; Thompson, William F.

doi:10.1007/978-1-4615-4199-8_1

Cited by 7 publications

(3 citation statements)

References 73 publications

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“…Differential translational regulation in plants can be mediated by RNA-regulatory motifs within the 5′- or 3′-UTR of the mRNA (Bailey-Serres, 1999; Petracek and Thompson, 2000). Examples of mRNA regions or elements have been reported for both environmentally and developmentally regulated transcripts.…”

Section: Discussionmentioning

confidence: 99%

Dynamic Light Regulation of Translation Status in Arabidopsis thaliana

Juntawong¹,

2012

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Light, a dynamic environmental parameter, is an essential regulator of plant growth and development. Light-regulated transcriptional networks are well documented, whereas light-regulated post-transcriptional regulation has received limited attention. In this study, dynamics in translation of cytosolic mRNAs were evaluated at the genome-level in Arabidopsis thaliana seedlings grown under a typical light/dark diurnal regime, shifted to darkness at midday, and then re-illuminated. One-hour of unanticipated darkness reduced levels of polysomes by 17% in a manner consistent with inhibition of initiation of translation. This down-regulation of translation was reversed within 10 min of re-illumination. Quantitative comparison of the total cellular population of transcripts (the transcriptome) to those associated with one or more 80S ribosome (the translatome) identified over 1600 mRNAs that were differentially translated in response to light availability. Unanticipated darkness limited both transcription and translation of mRNAs encoding components of the photosynthetic machinery. Many mRNAs encoding proteins associated with the energy demanding process of protein synthesis were stable but sequestered in the dark, in a rapidly reversible manner. A meta-analysis determined these same transcripts were similarly and coordinately regulated in response to changes in oxygen availability. The dark and hypoxia translationally repressed mRNAs lack highly supported candidate RNA-regulatory elements but are characterized by G + C-rich 5′-untranslated regions. We propose that modulation of translation of a subset of cellular mRNAs functions as an energy conservation mechanism.

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Section: Discussionmentioning

confidence: 99%

Dynamic Light Regulation of Translation Status in Arabidopsis thaliana

Juntawong¹,

2012

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“…Abler and Green, 1996; Sullivan and Green, 1993). Often, cis ‐regulatory elements are located at the 5′ end or within the 5′ UTR of the message, and are responsible for the establishment of a secondary structure (Dickey et al ., 1998; Petracek and Thompson, 2000; Petracek et al ., 1997; Sherameti et al ., 2002; Yamamoto et al ., 1995). The 5′ UTR of the (γ‐glutamylcysteine synthase mRNA, for instance, which is efficiently translated in response to cellular redox signals, is recognized by a protein.…”

Section: Discussionmentioning

confidence: 99%

“…It has been reported that polyribosome loading of messages for photosynthesis proteins represents an efficient and rapid mechanism to adapt protein synthesis to environmental changes (cf. Petracek and Thompson, 2000). Therefore, we tested whether cytokinin controls polyribosome loading of the nuclear‐encoded messages for the plastid ATP synthase subunits γ, δ and CF 0 II.…”

Section: Introductionmentioning

confidence: 99%

Cytokinin stimulates polyribosome loading of nuclear‐encoded mRNAs for the plastid ATP synthase in etioplasts of Lupinus luteus: the complex accumulates in the inner‐envelope membrane with the CF₁ moiety located towards the stromal space

et al. 2004

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SummaryThree of the nine subunits of the plastid ATP synthase, including the subunit of the CF 1 moiety (gene AtpC ), are encoded in the nucleus. Application of cytokinin to etiolated lupine seedlings induces polyribosome association of their mRNAs. This appears to be speci®c as no such regulation was observed for messages for three ribosomal proteins. Cytokinin-mediated polyribosome loading was also observed for the spinach AtpC message in etiolated transgenic tobacco seedlings. Analysis of various spinach AtpC mRNA derivatives uncovered that the 5 H untranslated region (5 H UTR) of this message is suf®cient to direct polyribosome loading, and that sequences at the 3 H end of the AtpC 5 H UTR, including an UC-rich motif, are crucial for this regulation. The increase in polyribosome loading of the AtpC message correlated with an increased synthesis of the polypeptide. The subunit, together with the ATP synthase complex, accumulates in the innerenvelope membrane with the CF 1 moiety located towards the stromal space of the etioplast. These results suggest that cytokinin promotes accumulation of the ATP synthase in the inner-envelope membrane of lupine etioplasts by stimulating the translation ef®ciency of their nuclear-encoded messages.

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Chalcogenides: Solid‐State ChemistryBased in part on the article Chalcogenides: Solid State Chemistry by Patricia M. Keane which appeared in theEncyclopedia of Inorganic Chemistry, First Edition.

Kanatzidis

2005

Encyclopedia of Inorganic Chemistry

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This article deals with the solid‐state chemistry of chalcogenides and describes mainly the developments during the past decade. The article is not exhaustive but is meant to give a broad set of examples of interesting compounds and solid‐state chemistry of these compounds so that the reader can obtain a reasonable and rounded view of the recent activities in this area. Further depth and additional information can be obtained from the available references.

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Post-Transcriptional Light Regulation of Nuclear-Encoded Genes

Cited by 7 publications

References 73 publications

Dynamic Light Regulation of Translation Status in Arabidopsis thaliana

Dynamic Light Regulation of Translation Status in Arabidopsis thaliana

Cytokinin stimulates polyribosome loading of nuclear‐encoded mRNAs for the plastid ATP synthase in etioplasts of Lupinus luteus: the complex accumulates in the inner‐envelope membrane with the CF₁ moiety located towards the stromal space

Chalcogenides: Solid‐State ChemistryBased in part on the article Chalcogenides: Solid State Chemistry by Patricia M. Keane which appeared in theEncyclopedia of Inorganic Chemistry, First Edition.

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Post-Transcriptional Light Regulation of Nuclear-Encoded Genes

Cited by 7 publications

References 73 publications

Dynamic Light Regulation of Translation Status in Arabidopsis thaliana

Dynamic Light Regulation of Translation Status in Arabidopsis thaliana

Cytokinin stimulates polyribosome loading of nuclear‐encoded mRNAs for the plastid ATP synthase in etioplasts of Lupinus luteus: the complex accumulates in the inner‐envelope membrane with the CF1 moiety located towards the stromal space

Chalcogenides: Solid‐State ChemistryBased in part on the article Chalcogenides: Solid State Chemistry by Patricia M. Keane which appeared in theEncyclopedia of Inorganic Chemistry, First Edition.

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Cytokinin stimulates polyribosome loading of nuclear‐encoded mRNAs for the plastid ATP synthase in etioplasts of Lupinus luteus: the complex accumulates in the inner‐envelope membrane with the CF₁ moiety located towards the stromal space