Post-transplant plasmablastic lymphoma of the skin

Nicol, I; Boyé, T.; Carsuzaa, F.; Feier, L.; Villette, A; Xerri, Luc; Grob, Jean-Jacques; Richard, M.‐A.

doi:10.1046/j.1365-2133.2003.05544.x

Cited by 58 publications

(36 citation statements)

References 9 publications

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“…Plasmablastic lymphomas are seen almost exclusively in the setting of HIV infection or other immune deficiencies. [170][171][172] Some of these cases had only skin lesions at presentation. Rare cases of primary cutaneous T-cell/histiocyte-rich B-cell lymphoma, characterized by the presence of large scattered B cells in a background of numerous reactive T cells, have been reported.…”

Section: Primary Cutaneous Diffuse Large B-cell Lymphoma Leg Typementioning

confidence: 99%

WHO-EORTC classification for cutaneous lymphomas

Willemze

Jaffe

Burg

et al. 2005

Blood

3,518

4,355

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Section: Primary Cutaneous Diffuse Large B-cell Lymphoma Leg Typementioning

confidence: 99%

WHO-EORTC classification for cutaneous lymphomas

Willemze

Jaffe

Burg

et al. 2005

Blood

3,518

4,355

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“…However, upon review, in fact, we found it to be the most common site for EoPL, with a total of 12 cases being identified from the available literature [6,16,17,20,21,22,23]. The other common sites include the stomach, skin, cervical lymph node and orbit, with a similar incidence [10,11,15,17,24,25,26,27,28,29,30,31,32,33,34]. A few cases of CNS involvement have also been reported [33,35].…”

Section: Discussion and Review Of The Literaturementioning

confidence: 98%

Extraoral Plasmablastic Lymphoma Detected Using Ascitic Fluid Cytology and Flow Cytometry: A Case Report with a Review of the Literature

Dorwal

Sachdev²,

Mishra³

et al. 2014

Acta Cytologica

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Background: Plasmablastic lymphoma (PL) is a relatively new category of lymphoma, which has been considered to be found predominantly in the oral cavity and has a strong association with HIV. Case: We report a case of extraoral/mesenteric PL detected using cytological examination of ascitic fluid assisted by flow cytometric (FC) analysis. The cells were positive for CD38, CD138, CD10, CD45 and CD56 and negative for CD3, CD19, CD20 and CD79a, with cytoplasmic lambda light-chain restriction. We also reviewed 67 cases of extraoral PL from the available literature and found them to be less often associated with HIV (than oral PL), occurring mostly in males aged 30-60 years, with the most common extraoral site being the anorectal region. Conclusion: A high index of suspicion at the level of the cytopathologist is imperative for identifying lymphoma cells in a body fluid. A rare entity like PL can also be diagnosed on cytology assisted by ancillary techniques (like FC), without the need for a biopsy. We also suggest that the minimum panel to diagnose PLs should include CD138, MUM-1, Ki-67, ALK-1, CD3, immunoglobulin light-chains, CD20 and PAX5.

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“…Th e lesion is characterized morphologically by blastic cells with a plasma cell immunophenotype. In recent years, this entity has also been described in individuals who have previously undergone a transplantation procedure, including kidney, heart, heart/lung, liver/small bowel, and bone marrow ( Table 1) (4,(19)(20)(21)(22)(23)(24). To our knowledge, the present report is the fi rst describing plasmablastic lymphoma following pancreatic transplantation.…”

Section: Discussionmentioning

confidence: 99%

“…Since its initial description, it has now become well established as an entity seen in HIV-negative individuals as well, albeit rarely (3). In 2003, the fi rst case of plasmablastic lymphoma in a posttransplant lymphoproliferative disorder (PTLD) was reported as a cutaneous leg ulcer (4). Since this original description, several additional cases have been reported following various solid organ and bone marrow transplantations.…”

mentioning

confidence: 99%