Posterior capsule opacification: Comparison of 3 intraocular lenses of different materials and design

Abstract

Patients with an AcrySof IOL developed significantly less PCO than those with a silicone or HSM PMMA IOL with a round-edged design.

Posterior capsule opacification after extra capsular cataract extraction in Indian rural population: Foldable acrylic vs poly (methyl-methacrylate) intraocular lenses a randomized clinical trial

“…The degree of PCO varies depending on the age at surgery, surgical technique retained soft lens matter, post-operative uveitis, IOL optic material, and IOL design. 7,8,[11][12][13][14] The inclusion of only normal eyes apart from senile cataract, the nature of the prospective randomized single surgeon design of this trial, and the use of standardized surgical procedure, and medication eliminate other explanations for our results. Therefore, the differences in PCO among the study groups can probably be ascribed to IOL material and design.…”

The Relationship between the Adhesion Characteristics of Acrylic Intraocular Lens Materials and Posterior Capsule Opacification

“…The materials and the edge design of IOLs are two important factors that influence the incidence of PCO [20,30,31] .…”

Hydrophobic acrylic and plate-haptic silicone intraocular lens implantation in diabetic patients

“…The most important of these features seems to be the square edge of the optic of the hydrophobic acrylic IOLs, which has been shown in experimental research and clinical studies of nondiabetic patients to inhibit migration of the LECs onto the posterior capsule and hence to prevent the development of PCO. [23][24][25][26][27] This was attributed to contact inhibition of LECs 28 or to a mechanical barrier effect. 29 Also, the haptic angulation, which is 10 degrees in the AcrySof IOL and 0 in the plate-haptic silicone IOL, together with the larger overall diameter of the former IOL, are other features that could play an important role in preventing migration of the LECs by creating and increasing posterior vaulting of the optic upon capsular contraction.…”