Postischemic Myocardial Stunning Is Superior to Transient Ischemic Dilation for Detecting Multivessel Coronary Artery Disease

Cardiac Magnetic Resonance Performs Better in the Detection of Functionally Significant Coronary Artery Stenosis Compared to Single-Photon Emission Computed Tomography and Dobutamine Stress Echocardiography

“…30 In SPECT, the combination of global and regional left ventricular function and perfusion can improve diagnostic performance compared to MPI alone. The post-stress acquisition of regional wall motion and thickening abnormalities, 31 and transient ventricular dilatation 32 caused by the persistence of post-ischemic stunning has been shown to be useful particularly in patients with MVD. The diagnostic performance of CMR and SPECT might be improved with these latest imaging techniques.…”

Comparison of Myocardial Perfusion Imaging Between the New High-Speed Gamma Camera and the Standard Anger Camera

“…3, 12 The current study showed a strong concordance (κ=0.815) in overall segments, but when these segments were categorized based on the 3 coronary territories, the concordance rate decreased, particularly in the right coronary territory (κ=0.774). In the segment related to the right coronary artery, a greater number of segments were rated as having more severe defects with the CZT camera as compared with the standard Anger camera ( Table 2).…”

“…In contrast to perfusion analysis, strongly positive correlations were observed in LV functional analysis such as for ejection fraction, measured either with the Anger or CZT camera. 12 In contrast to some of the aforementioned reports, 5, 18 we evaluated a greater number of patients (n=150) with known or suspected coronary artery disease using a 3-head gamma camera system with a 15-min scan time as a standard. The dose of 99 m Tc-tetrofosmin was lower, particularly at rest with 740 MBq as compared with the previous studies, because the body size of the Japanese patients was taken into account.…”

The Less Embraces the Greater in Detecting Multiple Coronary Artery Disease

“…First, taken together with other sets of data that conventional diagnosis via multi-territorial malperfusion alone provides a similar sensitivity of 77%, but lower specificity of 55%, for predicting multiple coronary ischemia, 9 and that these values are not improved even in combination with an increased TID ratio, 9 the criteria proposed here (ie, PMS together with multi-territorial ischemia) has sufficient power of detecting broad and multiple CAD and might give substantial priority to stress SPECT test as a first-line extensive noninvasive examination following routine screening tests to diagnose multiple CAD in the clinical setting. In fact, invasive CAG is currently still serving as the best standard for detecting coronary structural stenosis because it can provide detailed and complicated information at once precisely, regardless of heart rate and arrhythmia.…”