Postmortem Diagnosis of Hypertonic Dehydration by Chemical Analysis of Vitreous Humor

Damian, Simona Irina; Nedelea, Paul; David, Sofia; Knieling, Anton; Moldoveanu, Sorin; Sandu, Ion; Iov, Catalin

doi:10.37358/rc.17.11.5947

Cited by 4 publications

(4 citation statements)

References 20 publications

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“…The concrete examples of pathologies determined by the intoxication with various substances determine the increase of the student's motivation to participate actively in the course and to understand the physico-chemical phenomena studied as well as the anatomical-physiological particularities presented during the course (Kaplan, 2019;Ciubara et al, 2018;Damian, David, Moldoveanu, Iov, Nedelea, Knieling & Sandu, 2017). L.J.…”

Section: Particularities Of Teaching Chemistry In Forensic Toxicologymentioning

confidence: 99%

Particularities of Medical Education in the Field of Forensic Toxicology. Studying Dangerous Chemical Agents in Forensic Research

Damian

Diac

Iov³

et al. 2019

RREM

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The various insufficiencies or even diseases generated by the intoxication with the various substances, affect the quality of life -both of the intoxicated person and of those in the social environment in which he lives and works. The present article aims to analyse a series of perspectives regarding the role and importance of studying chemistry in the professional training of future doctors, especially residents in the field of forensic medicine.

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Section: Particularities Of Teaching Chemistry In Forensic Toxicologymentioning

confidence: 99%

Particularities of Medical Education in the Field of Forensic Toxicology. Studying Dangerous Chemical Agents in Forensic Research

Damian

Diac

Iov³

et al. 2019

RREM

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“…To its high toxicity is added the danger of going unnoticed, as it is odourless, colourless and not irritating for mucous membranes, not announcing its lethal presence to unnoticed people exposed [1,2]. The biochemical mechanism of the poisoning effect is very different than with other substances [3][4][5][6][7][8].…”

mentioning

confidence: 99%

Study of Carbon Monoxide Intoxication in Fire Victimis

David¹,

Knieling²,

Scripcaru³

et al. 2018

Rev. Chim.

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Carbon monoxide poisoning is the leading cause of mortality and morbidity of toxic origin in the world. Its insidious and polymorphic symptomatology makes it difficult to diagnose. It occurs accidentally, because of non-supervised domestic fires, or in fire victims. In fire victims, in particular, the differential diagnosis between carbon monoxide gas poisoning, inhalation of other toxic products of combustion like cyanide, oxygen deprivation, thermal burns and shock due to burns as a cause of death is not an easy task. The authors examined 107 fire victims that were autopsied at the Forensic Medicine from Iasi, Romania, in the last 10 years (2007-2016). Most cases were males (69.16%), young (0-9 years) or older than 60 with a burned surface of 91-100% in 68.22% of cases. Blood samples from the cadavers were collected in all cases in order to analyse carboxyhaemoglobin concentration and haemolysis. Toxicological analysis revealed a carboxyhaemoglobin level of maximum 95% but the majority of cases (70.72%) had a concentration inferior to 50%. An inverse correlation was identified between carboxyhaemoglobin concentration and haemolysis, an indicator of heat dissociation. Our study proves that many fire victims may die because of carbon monoxide intoxication prior to the extent of burns at a lethal potential.

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“…The binding of carbon monoxide to cytochrome oxidase also interferes with aerobic metabolism and with efficient adenosine triphosphate (ATP) synthesis [11]. CO, along with nitric oxide (NO), appear to modulate intracellular cGMP levels, platelet aggregation, and smooth muscle relaxation [12]. Overall, CO has a lower affinity for soluble guanylyl cyclase (a heme protein) than NO ( fig.…”

mentioning

confidence: 99%

An Unusual Case of Accidental Carbon Monoxide and Ethanol Intoxication in Two Commorientes Deaths

Dumbrava¹,

Radu²,

Iov³

et al. 2018

Rev. Chim.

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Death by intoxication represents an important cause of violent deaths which could be easily prevented. Accidental ethanol and carbon monoxide intoxications produce the most frequent causes of violent deaths among civilians in Romania. To provide an insight in these types of deaths and to bring attention upon the clinical and biological manifestations as well as of the typical morphologically findings, the authors present a strange case of fatal intoxication due to carbon monoxide in an 88 years old male, found in his bed. Moreover, because of the simultaneous death of the male�s wife in the attic of the house, with ethanol intoxication, we would also like to bring attention to the juridical notion of commorientes, since in the establishing of its constituting characteristics the forensic expertise plays a decisive role.

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Postmortem Diagnosis of Hypertonic Dehydration by Chemical Analysis of Vitreous Humor

Cited by 4 publications

References 20 publications

Particularities of Medical Education in the Field of Forensic Toxicology. Studying Dangerous Chemical Agents in Forensic Research

Particularities of Medical Education in the Field of Forensic Toxicology. Studying Dangerous Chemical Agents in Forensic Research

Study of Carbon Monoxide Intoxication in Fire Victimis

An Unusual Case of Accidental Carbon Monoxide and Ethanol Intoxication in Two Commorientes Deaths

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