2002
DOI: 10.1006/brbi.2001.0642
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Postnatal Lipopolysaccharide-Induced Illness Predisposes to Periodontal Disease in Adulthood

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Cited by 89 publications
(97 citation statements)
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References 39 publications
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“…However, at least one of these studies used the hypersensitive Fischer 344 rat (Walker et al, 2004), indicating a possible strain difference on behavioral consequences of neonatal LPS exposure. Also, in each of these studies, the LPS was delivered at earlier time points P3 and/or P5 (Walker et al, 2004;Breivik et al, 2002;Anseloni et al, 2005). It is possible that a significant effect on behavior could be seen with an early-life LPS challenge at a different time point to those tested here, or that a different behavioral test would be more suitable for identifying differences.…”
Section: Lps Does Not Significantly Alter Adult Behavior In the Elevamentioning
confidence: 99%
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“…However, at least one of these studies used the hypersensitive Fischer 344 rat (Walker et al, 2004), indicating a possible strain difference on behavioral consequences of neonatal LPS exposure. Also, in each of these studies, the LPS was delivered at earlier time points P3 and/or P5 (Walker et al, 2004;Breivik et al, 2002;Anseloni et al, 2005). It is possible that a significant effect on behavior could be seen with an early-life LPS challenge at a different time point to those tested here, or that a different behavioral test would be more suitable for identifying differences.…”
Section: Lps Does Not Significantly Alter Adult Behavior In the Elevamentioning
confidence: 99%
“…One major factor in this may be the timing of the early challenge. We have previously shown that LPS given at P14 does not affect basal exploration of the elevated plus maze, an assessment of activity and anxiety; however, two studies which involved an endotoxin exposure at earlier time points have demonstrated effects on plus maze responses in adults (Breivik et al, 2002;Walker et al, 2004). Thus, we also assessed activity and anxiety responses in the elevated plus maze.…”
Section: Introductionmentioning
confidence: 97%
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“…For monitoring home cage activity, an infrared sensor controlled recording system (model No. E61-01/08; Coulbourn Instruments, Allentown, PA, USA) was used as described previously (23). This test is based on infrared detection of number and time of movements and it is useful to screen for differences in circadian rhythm.…”
Section: Determination Of Motor Functions (Accelerod Test) and Circadmentioning
confidence: 99%
“…show that the chemical modulation of the HPA axis, or directly the effect of physical chronic stress during pregnancy are responsible for a higher progression of periodontitis induced in adulthood 11,12 .…”
Section: Introductionmentioning
confidence: 99%