Postoperative Analgesia With Transdermal Diclofenac Versus Intramuscular Diclofenac – A Comparative Study

Samal, Soumya; Jena, Saubhagya Kumar; Behera, Basanta Kumar

doi:10.14260/jemds/706

Cited by 3 publications

(3 citation statements)

References 13 publications

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“…The premise of successful treatment is based not only on the correct operative technique but also on the prevention and management of postoperative complications such as pain and swelling. [ 1 ] The international association for the study of pain has defined pain as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage.”[ 2 ]…”

Section: Introductionmentioning

confidence: 99%

“…Over the years, opioids have been administered to allay anxiety and to reduce pain associated with surgery. [ 2 ] Nonsteroidal anti-inflammatory drugs (NSAIDs), commonly prescribed in dental practice for the management of pain,[ 3 ] are among the most frequently prescribed drugs worldwide. [ 4 ] There are various routes of analgesic administration, among which oral analgesics is commonly prescribed for the management of pain.…”

Section: Introductionmentioning

confidence: 99%

“…[ 8 ] Transdermal patches have been developed as innovative topical delivery systems for diclofenac. [ 6 ] The advantages of this route include painless, nonirritant, increased bioavailability, and it can be applied for 24 h.[ 2 ]…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Efficacy of transdermal diclofenac patch as an analgesic following premolar extractions in orthodontic patients

Talnia

Fry

Sharma

et al. 2020

Ann Maxillofac Surg

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Aim: The aim of the study was to evaluate the efficacy of transdermal diclofenac patch versus oral diclofenac tablet as analgesic following premolar extractions in orthodontic patients. Materials and Methods: Thirty-three symmetrical pairs of indicated premolars (either first or second) were included for the present study. Each patient was given either transdermal diclofenac sodium patch 100 mg once a day or oral diclofenac tablet 50 mg twice a day for 3 days after the extraction. Pain was assessed by a 10-point visual analog scale and 4-point verbal rating scale given to the patient for each day for 3 days after the extraction. All observational findings were recorded, tabulated, and analyzed statistically. Results: This study consisted of 33 patients with a mean age of 18.73 ± 3.677 years. Out of 33 patients included in this study, 5 were male and 28 were female. The result of the study showed that consecutive postoperative days transdermal diclofenac patch was slightly more efficient in controlling the postoperative pain in the extraction done for the orthodontic purpose than diclofenac oral tablet, however statistically no significant difference was observed using Chi-square test ( P > 0.05). Conclusion: Transdermal diclofenac patch showed potential analgesic modality for the management of mild-to-moderate intensity pain in premolar orthodontic extraction, with lower incidence of systemic adverse effects. However, cost and availability may limit the use of transdermal patch.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Efficacy of transdermal diclofenac patch as an analgesic following premolar extractions in orthodontic patients

Talnia

Fry

Sharma

et al. 2020

Ann Maxillofac Surg

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Appraisal of efficacy of transdermal diclofenac patch for postoperative analgesia in maxillofacial trauma

Shenoi

Neha

2015

International Journal of Oral and Maxillofacial Surgery

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Efficacy of diclofenac transdermal patch versus injection as post-cesarean analgesia: A clinical, comparative, single-blind randomized control trial

Dhamankar,

Javali,

Sunkad

2024

WJWCH

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Objectives: Post-operative pain is a common problem following cesarean delivery. The efficacy of topical application of diclofenac in alleviating pain has not been well established. We aim to evaluate the analgesic effect of transdermal diclofenac patch and compare it with the injectable form. Material and Methods: This is a prospective, randomized, single-blind, and placebo-controlled study. The study protocols and ethical considerations were adhered fully. Parturient women (n = 90) undergoing cesarean section were randomized into two equal groups: the transdermal diclofenac patch (Group A) and the injectable diclofenac (Group B). The surgery was performed under spinal anesthesia. The participant’s demographic data, clinical data, pain relief data collected, compiled, and analyzed using the Statistical Package for the Social Sciences 20. The post-operative pain was scored using Visual Analog Scale. Pain relief scores were compared between the groups using Mann–Whitney U-test and Wilcoxon matched-pair test. Results: The participants match in demographic and clinical characters. The pain relief scores at 12 h was – 3.10 ± 0.74 and 3.04 ± 0.21 respectively while at 24 hours was – 2.48 ± 0.51 and 2.09 ± 0.29 respectively in Group A and Group B. The difference between Group A and Group B was statistically significant (P = 0.0022). The pain relief scores in both groups match was statistically significant at 6–24 h and 6–48 h (P = 0.0001, 0.0001). Conclusion: Diclofenac transdermal patch gives equal pain relief as that of routine injectable formulation.

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Postoperative Analgesia With Transdermal Diclofenac Versus Intramuscular Diclofenac – A Comparative Study

Abstract: BACKGROUND:The search for an ideal drug for postoperative analgesia is ongoing. Diclofenac is commonly used drug for this purpose in different routes. AIMS: To compare the efficacy of transdermal diclofenac with intramuscular diclofenac for postoperative analgesia.

Cited by 3 publications

References 13 publications

Efficacy of transdermal diclofenac patch as an analgesic following premolar extractions in orthodontic patients

Efficacy of transdermal diclofenac patch as an analgesic following premolar extractions in orthodontic patients

Appraisal of efficacy of transdermal diclofenac patch for postoperative analgesia in maxillofacial trauma

Efficacy of diclofenac transdermal patch versus injection as post-cesarean analgesia: A clinical, comparative, single-blind randomized control trial

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