Postoperative endophthalmitis: Establishment and results of a national registry

Abstract

Postoperative endophthalmitis remains a serious complication of intraocular surgery, although the prognosis depends greatly on the microbe isolated. Common guidelines should be established regarding clinical and microbiological diagnosis and treatment. Further improvement of the registry would make it a suitable platform for evaluating prophylactic treatments.

Six-year incidence of endophthalmitis after cataract surgery: Swedish national study

“…2,6-9 Since 1999, the Swedish endophthalmitis rate has been steadily parked at 0.05%; that is, at the lower end of the incidence range reported in large-scale studies from various countries. 2,3,6,10,11 We believe that the universally adopted use of prophylactic intracameral cefuroxime in our country has contributed to the favorable situation.The objective of this study was to gather data on postoperative endophthalmitis after cataract surgery in Sweden from 2005 through 2010 with the aim of describing the epidemiology, morbidity, and risk factors. In addition, cases given preoperative and/or postoperative topical antibiotics as an add-on to the intracameral regimen were compared with cases that received intracameral antibiotics only.…”

“…2,[6][7][8][9] Since 1999, the Swedish endophthalmitis rate has been steadily parked at 0.05%; that is, at the lower end of the incidence range reported in large-scale studies from various countries. 2,3,6,10,11 We believe that the universally adopted use of prophylactic intracameral cefuroxime in our country has contributed to the favorable situation.…”

The in vitro antimicrobial activity of silicone oils used in ophthalmic surgery

“…[12][13][14][15] ). Sandvig et al 16 evaluated 111 cases of postoperative endophthalmitis, of which 80 (72%) were culture-positive. The detected etiologic agents were mostly (in 75 cases) gram-positive bacteria (coagulase-positive and -negative staphylococci, streptococci, enterococci, anaerobic propionibacteria); the rare gramnegative isolates included enterobacteria, Haemophilus influenzae, Moraxella sp.…”

Comparison of cytotoxicity of fluoroquinolone antimicrobial eye drops and its effect on their bioavailability

“…Проведённые Таблица 4 Данные качественной оценки состояния клеток эпителия роговицы у пациентов 2-й группы (Моксифлоксацин) по дан-ным конфокальной микроскопии ранее зарубежные исследования показали, что фторхинолоны в различной степени способны подавлять пролиферацию кератоцитов [14] и при высоких концентрациях оказывать цитотоксиче-ский эффект на эпителий и эндотелий роговицы [12]. В ранних работах по оценке цитотоксично-сти фторхинолонов было установлено, что ци-профлоксацин обладал наименьшей цитотоксич-ностью по отношению к роговичному эпителию в сравнении с норфлоксацином и офлоксацином, а также гентамицином и тобрамицином [9].…”