Postoperative Pulmonary Complications

King, Donald S.

doi:10.1001/jama.1933.02740010023006

Cited by 15 publications

(4 citation statements)

References 13 publications

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“…Prospective studies have described an incidence of 6-21%. [2][3][4][5] The causes of postoperative pulmonary infections are multifactorial but depend on clearance of lung secretions. This requires effective coughing and ciliary transport of respiratory mucus.…”

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confidence: 99%

Comparison of isoflurane with propofol on respiratory cilia

Raphael

Butt

1997

British Journal of Anaesthesia

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We have investigated the effects of two techniques of clinical anaesthesia on human respiratory cilia by measuring cilia beat frequency of nasal tissue. In a randomized, controlled study, 13 patients undergoing either inhalation anaesthesia with isoflurane or total i.v. anaesthesia with propofol and alfentanil had nasal ciliated epithelial samples removed at the beginning and after 1 h of anaesthesia. Mean cilia beat frequency in the group anaesthetized with isoflurane changed significantly from 11.5 (95% confidence interval (CI) 10.7-12.2) Hz to 9.1 (8.1-10.1) Hz after anaesthesia whereas in the group anaesthetized with propofol and alfentanil there was a change from 11.5 (10.7-12.2) Hz to 11.0 (10.2-11.8) Hz (ns). The difference between the anaesthetic agents on cilia beat frequency was significant (MANOVA, P < 0.01). These data suggest that different anaesthetic agents may impair respiratory defence mechanisms to differing extents.

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confidence: 99%

Comparison of isoflurane with propofol on respiratory cilia

Raphael

Butt

1997

British Journal of Anaesthesia

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“…Every other patient, in the subgroups of each sex, was treated." [22] He continued: "This alternation gave, for instance, a group of men who had had operations on the stomach and who had had hyperventilation induced, to compare with an equal number of men who had had operations on the stomach but who had not had hyperventilation induced. … Thus, statistics were available for male and female cases, treated and untreated, in the different groups of abdominal operations and hernia repair.…”

Section: Matching and Stratification In Alternate Allocation Studiesmentioning

confidence: 99%

Richard Cabot, pair-matched random allocation, and the attempt to compare like with like in the social sciences and medicine: Part 2: The context of medicine and public health

Welsh,

Podolsky,

Zane

2021

CrimRxiv

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“…4,5 Efforts to identify the risk factors that may be associated with these PPCs have been done since the 1930s. 6 The preoperative evaluation of a patient's pulmonary status becomes necessary in view of high incidence of PPCs. 3,7 As of today, there have been very few studies that have been done to develop a predictive model for PPCs, which affects the clinician's ability to predict and plan strategies to prevent PPCs in high-risk groups.…”

Section: Introductionmentioning

confidence: 99%

Study of risk, incidence and mortality associated with postoperative pulmonary complications using assess respiratory risk in surgical patients in catalonia score

2019

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Background: Postoperative pulmonary complications (PPCs) are one of the major complications that are seen in patients undergoing surgeries and are also a significant cause of increased duration of hospital stay and mortality. Owing to their high incidence the present study was done to assess the risk and incidence of PPCs using the assess respiratory risk in surgical patients in catalonia (ARISCAT) score and to observe the mortality related to PPCS.Methods: The study was done at a tertiary care center over a period of three month and 150 patients were involved. The patients were the categorized into three risk groups and were observed for development of any PPCs.Results: Out of the 150 patients that were studied, 29 developed some form of PPC. 21 out of these 29 (72.41%) patients were from the high-risk category. 11 out of the 29 patients died in a span of 30 days. Pneumonia was seen to be the most common PPC.Conclusions: ARISCAT score can be useful as a preoperative evaluation tool to classify patients into risk groups and predict the development of PPC in the high-risk groups and to take measures to reduce the risk of PPCs. We conclude from our study that anemia, emergency surgery and surgery with duration of more than 3 hours were significant factors contributing to both the incidence and mortality of PPCs irrespective of the risk group.

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Postoperative Pulmonary Complications

Cited by 15 publications

References 13 publications

Comparison of isoflurane with propofol on respiratory cilia

Comparison of isoflurane with propofol on respiratory cilia

Richard Cabot, pair-matched random allocation, and the attempt to compare like with like in the social sciences and medicine: Part 2: The context of medicine and public health

Study of risk, incidence and mortality associated with postoperative pulmonary complications using assess respiratory risk in surgical patients in catalonia score

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