Postpartum Psychosis and the Pineal Gland

Sandyk, Reuven

doi:10.3109/00207459108999763

Cited by 4 publications

(5 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A marked reduction in plasma melatonin levels may lead to acute dysinhibition of limbic dopaminergic activity in the postpartum period resulting in increased dopamine release and the stimulation of supersensitive dopamine receptors. In keeping with this hypothesis, the use of bright light and administration of melatonin have been suggested as possible treatment strategies (26).…”

mentioning

confidence: 99%

“…Wieck et al (25), who studied growth hormone response to apomorphine, concluded that postpartum psychosis was associated with increased sensitivity of dopamine receptors. A precipitous fall in the level of melatonin after parturition has also been hypothesized to play an etiological role by virtue of its antidopaminergic effects (26). Melatonin may act as an endogenous Ôantipsychotic hormoneÕ by blocking presynaptic dopamine release in the limbic system.…”

mentioning

confidence: 99%

“…A precipitous fall in the level of melatonin after parturition has also been hypothesized to play an etiological role by virtue of its antidopaminergic effects (26). In keeping with this hypothesis, the use of bright light and administration of melatonin have been suggested as possible treatment strategies (26). A marked reduction in plasma melatonin levels may lead to acute dysinhibition of limbic dopaminergic activity in the postpartum period resulting in increased dopamine release and the stimulation of supersensitive dopamine receptors.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Sleep loss and postpartum psychosis

2003

View full text Add to dashboard Cite

Postpartum psychosis is a rare but severe psychiatric disorder. Its diagnostic status remains controversial, but several studies have shown that the majority of patients who develop psychosis immediately following childbirth suffer from bipolar disorder. The pathophysiology of postpartum psychosis is poorly understood, but factors such as primiparity, difficult labor, genetic predisposition, and hormonal changes have been suggested as etiological factors. This paper reviews the literature on the relationship of sleep disruption and postpartum psychosis. It is argued that sleep loss resulting from the interaction of various putative causal factors may be the final common pathway in the development of psychosis in susceptible women. Clinical significance of these findings, including strategies to prevent postpartum psychosis, are discussed and suggestions are made for future research directions.

show abstract

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Sleep loss and postpartum psychosis

2003

View full text Add to dashboard Cite

show abstract

“…Hopwood (1 92 7 ) provides four case studies of women who committed infanticide and describes different forms ofperipueral psychoses (unipolar [psychotic or nonpsychotic] depression, bipolar depression, and schizophrenia [dementia praecox]). Delusional thoughts may also involve ideas that the baby is dead or defective (Sandyk, 1992). Delusional thoughts may also involve ideas that the baby is dead or defective (Sandyk, 1992).…”

Section: Impact On Mother-child Bonding and Potential Harm To Infantmentioning

confidence: 99%

“…In a more recent description, Kaplan and Sadock (I 985) note that mothers experiencing peripueral psychosis may experience auditory hallucinations instructing them to lull their child. Delusional thoughts may also involve ideas that the baby is dead or defective (Sandyk, 1992). Davidson and Robertson (1985), in a longitudinal study of 82 patients who were treated for various postpartum psychiatric disorders, found the incidence of probable infanticide in their population to be 4%.…”

Section: Impact On Mother-child Bonding and Potential Harm To Infantmentioning

confidence: 99%

Should postpartum mood disorders be given a more prominent or distinct place in the DSM‐IV?

Purely

Frank

1993

Depression

View full text Add to dashboard Cite

In this review we consider the literature on postpartzcm psychosesas wellas on nonpsychotic postpartum depression with a goal of determining how such disorders shouId be categorized in DSM-N. We concIude that the majority of postparrum psychoses are affective in nature and that, despite the observation of '%onjhon" in many such presentations, the symptom picture is not suflciently unique to wart-ant a separate diagnostic category. We could $nd no evidence of unique presentation of non-psychotic postpartum depression. Nonetheless, because of the unique complications associated with postpartzcm disorders (e.g., disruption of the mother-infant bond, infanticide), we recommend that postpamm presentations be given a more prominent place in the text of DSM-IV and that a course spea@r, "post pa. Eum onset," be applied to major depressive or manic/hypmnis epicodes in Bipolar I, Bipolar 11, or Major Depressive Disorder, or to Acute Psychotic Disorder when appropriate . Depression 1:59-70 (1993). 0 1993 WiIeyLks, Inc.

show abstract