The psychological pressure of college teachers has become a social problem that the whole society pays close attention to. In the overall progress of our country's social changes and higher education reforms, university teachers are under tremendous psychological pressure, especially female physical education teachers in universities. The psychological pressure on their frequency or intensity is greater than before. Psychological pressure directly affects the physical and mental health of female physical education teachers in colleges and universities, and affects their lives to varying degrees. The quality of work affects the healthy development of students and the development of education as a whole. Therefore, it is of great significance in practice to analyze the current situation and causes of the psychological pressure of college teachers and propose effective coping strategies. This article is based on the big data-based research on the causes and countermeasures of female physical education teachers in colleges and universities to study the psychological pressure of female physical education teachers and countermeasures. Then use the questionnaire survey method to study the causes and countermeasures of the psychological pressure of female physical education teachers in colleges and universities, and provide the basis for the systematic modeling of the psychological pressure of colleges and universities through the analysis of the results. According to the survey results, the main reason for psychological pressure comes from job competition, which accounts for as high as 48%, and the pressure on job requirements and knowledge reserves is comparable. The countermeasures to the psychological pressure of female physical education teachers in colleges and universities are mainly to strengthen the training of teachers, accounting for about 40% of the total. Then, compared with teachers in other courses, physical education teachers have relatively strong job competition, and female teachers are relatively more competitive. The psychological pressure with male teachers is greater, which requires schools to implement human-oriented management of teachers, accounting for about 36%.