Potensi Krim Ekstrak Etanol Daun Stroberi (Fragaria x ananassa var Duchesne) sebagai Tabir Surya

Abstract

Ekstrak daun stroberi dilaporkan memiliki aktivitas tabir surya yang baik. Formulasi sediaan yang baik menjadi hal yang diperlukan untuk tahapan berikutnya. Penelitian ini bertujuan untuk mengetahui mutu fisik dari sediaan krim dan menentukan nilai SPF krim ekstrak etanol daun stroberi (Fragaria x ananassa var duchesne) sebagai tabir surya.
 Metode ekstraksi yang digunakan adalah refluks dengan pelarut etanol 96%. Analisis kandungan ekstrak dilakukan dengan kromatografi lapis tipis (KLT). Konsentrasi ekstrak yang digunakan untuk membuat krim tabir surya adalah 0,250% ; 0,500% dan 1,000%. Evaluasi yang dilakukan pada sediaan adalah uji mutu fisik, uji stabilitas sediaan dan aktivitas tabir surya baik in vivo dengan uji iritasi pada kulit manusia dan in vitro dengan spektrofotometri UV-Vis.
 Hasil penelitian ekstrak etanol daun stroberi didapatkan rendemen sebanyak 20,5% dan uji KLT menunjukan bahwa ekstrak daun stroberi positif mengandung flavonoid dan tanin. Krim ekstrak etanol daun stroberi yang paling baik pada konsentrasi 1,000% dengan nilai SPF sebesar 52,90.

Potensi dan Stabilitas Emulgel Ekstrak Etanol Daun Strawberry (Fragaria x ananassa var Duchesne) Sebagai Tabir Surya

“…The flavonoid TLC test showed that the Rf value of extract was 0.68 and the standard Rf of quercetin was 0.68, while TLC for tannins obtained the Rf value of extract 0.6 and standard Rf of gallic acid of 0.6. This is in accordance with research by Putri 3 .…”

“…The strawberry leaf extract emulgel formulation was prepared using variations in the extract concentration, namely 0.25%, 0.50%, and 1%. The selection of concentration variations was based on previous research, namely making emulsion preparations of ethanol extract of strawberry leaves with a concentration of 0.50%, resulting in an SPF value of 41.20 ± 0.072 3 .…”

“…This means that the difference in extract concentration does not affect the pH of the preparation. Previous studies have had a pH value of 7.9-8.1 in cream with ethanol extract from strawberry leaves 3 . This means that the emulgel is more acidic than the cream.…”

“…This result is better than previous studies on cream preparations. The ethanol extract cream of strawberry leaves has a dispersion power that does not meet the requirements, which ranges from 3-4 cm 3 . The results of the homogeneity examination are as expected.…”

“…This study formulated an emulgel sunscreen using the active substance of the ethanol extract of strawberry leaves with different concentrations. Previous research has carried out the ethanol cream formulation of strawberry leaves with a concentration of 0.50%, giving an ultra SPF value of 41.20 3 , and 1,00 % giving an ultra SPF value of 52.9 4 , Emulgel formula with 1% cinnamon bark extract 5 , 5 and 10 % guava leaves extract 6 as the active ingredient showed stable emulgel results. The novelty of this research is the choice of emulgel preparation.…”