Potential anti-inflammatory bioactives from medicinal plants of Western Ghats, India

Protective effects of crude and alkaloidal extracts of Tamarindus indica against acute inflammation and nociception in rats

“…This study showed that alkaloids are known to be the active component to relieve pain which is in accordance with previous study [24]. There are some reports on the role of tannins and flavonoids in antinociceptive activity [3].…”

“…of crude and alkaloidal extract, respectively. The increase in volume (cm 3 ) of the hind paw was measured with a LETICA digital plethysmometer at 20 min interval for a period of 2 h. Control rats received an equivalent amount of normal saline with sodium diclofenac (20 mg/kg body weight) served as reference. The percentage inhibition of oedema was calculated for each extract.…”

“…Inflammation is a defence mechanism by host against infections, foreign substances and tissue injury by activation of the cellular immune responses that stimulates various cytokines and nitric oxide which are known as pro-inflammatory mediators [2]. Excessive production of inflammatory mediators could, however, result in a chronic disease condition such as autoimmune disease and rheumatoid arthritis with features of redness, swelling, pain transmitted by peripheral or central nerves [3].…”

Chemical composition and anti-inflamatory, anti-nociceptive and antipyretic activity of rhizome essential oil of Globba sessiliflora Sims. collected from Garhwal region of Uttarakhand

“…Inflammation could result in a chronic stage which may indicate a factor of pathogenesis. A self defence mechanism may cause inflammation in primary phase which can be treated with chemotherapic agents to treat and eliminate symptoms and disease (Shailasree et al, 2012).…”

High-Throughput Screening by In silico Molecular Docking of Eryngium Foetidum (Linn.) Bioactives for Cylcooxygenase-2 Inhibition

“…According to the World Health Organization (WHO), poverty and lack of access to modern medicine leads the 65% to 80% of the world population in developing countries to critically depend on plants for primary health care. [2][3][4] Eryngium foetidum Linn., a tropical perennial and annual herb of the family Apiaceae with a pungent unique aroma is widely used in herbal medicines and is beneficial in the treatment of a number of ailments. 5,6 Studies have reported the use of E. foetidum in treatment of several antiinflammatory disorders.…”