Potential Antibacterial Activity of Hibiscus rosasinensis Linn  Flowers Extracts

Elaleem, Eman A. Sobhy Khadiga G. Abd; Elaleem, Hagir G. Abd

doi:10.20546/ijcmas.2017.604.132

Cited by 5 publications

(15 citation statements)

References 9 publications

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“…The maximum yield of extract (18.41 g/100 g) was found from Hibiscus rosa‐sinensis and the minimum from Zingiber officinalis (10.22 g/100 g). Aqueous extract yield depends on the amount of extractable polar compounds in plant materials (Sobhy et al., 2017 ; Sultana et al., 2007 ).…”

Section: Resultsmentioning

confidence: 99%

“…Various medicinal plants and herbs have long been recognized as a chief natural product source and are therapeutically effective against oxidative stress and obesity (Chien et al., 2016 ; Gomathi et al., 2008 ; Ismail, 2014 ; Sobhy et al., 2017 ; Priya & Veeranjaneyulu, 2016 ; Sultana et al., 2007 ). Due to fewer side effects in comparison with synthetic drugs, herbal teas (hot decoction, infusions, and herbal drinks), including lemon, hibiscus, ginger, mint, and cardamom teas, are some of the well‐known beverages.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of polyphenol‐rich traditional herbal teas on obesity and oxidative stress in rats fed a high‐fat–sugar diet

Iftikhar

Hussain

Chatha

et al. 2022

Food Science & Nutrition

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effects of polyphenol‐rich traditional herbal teas on obesity and oxidative stress in rats fed a high‐fat–sugar diet

Iftikhar

Hussain

Chatha

et al. 2022

Food Science & Nutrition

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“…The extracted purified compounds were fully characterized and identified by 1 H NMR, 13 C NMR, and GC−MS analysis. The spectra of the unidentified isolated compounds were compared with the spectra of the identified compounds in the library.…”

Section: Characterization Of Isolated Compoundsmentioning

confidence: 99%

“…The fabulous flowers of H. rosa-sinensis enjoy significant status in folk medicine throughout the world and comprises thiamine, riboflavin, citric acid, apigenidin, oxalic acid, quercetin, pelargonidin, ascorbic acid, and niacin. 16 Due to the presence of these bioactive compounds, the splendid flowers of H. rosasinensis own numerous biological and pharmaceutical activities like anti-infectious, antioxidant, antifungal, antimicrobial, antiinflammatory, antipyretic, antidiarrheic, 13 anticonvulsants, antidiabetic, antifertility, and antihyperlipidemic activity. 17 Its therapeutic volubility has been declared in folk medications to cure a variety of ailments, e.g., all types of inflammation, 18 cough, fever, decoction given in bronchial catarrh, 19 dysentery, venereal diseases, cancerous swellings, 20 urinary infection, 19 and ulcer.…”

Section: Introductionmentioning

confidence: 99%

Plant-Based Bioactive Phthalates Derived fromHibiscus rosa-sinensis: As In Vitro and In Silico Enzyme Inhibition

Yasmin,

Nazli,

Shafiq

et al. 2023

ACS Omega

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Hibiscus rosa-sinensis is an attractive, ever-blossoming, and effortlessly available plant around the globe. The fabulous flowers of H. rosa-sinensis enjoy a significant status in folk medicine throughout the world and comprise a range of phyto constituents due to which this splendid flower owns numerous biological and pharmaceutical activities like antioxidant, antifungal, antimicrobial, anti-inflammatory, antipyretic, antidiabetic, and antifertility activity. Considering this, column chromatographic isolation of the phytoconstituents of ethyl acetate fraction of the flowers of H. rosa-sinensis was performed. A series of five phthalates including Di- n -octyl phthalate ( HR1 ), ditridecyl phthalate ( HR2 ), 1-allyl 2-ethyl phthalate ( HR3 ), diethyl phthalate ( HR4 ), and bis (6-methylheptyl) phthalate ( HR5 ) were isolated. The structures of the isolated phthalates were elucidated by gas chromatography–mass spectrometry, 1 H NMR, and 13 C NMR. In silico and in vitro antidiabetic and antioxidant potential and DFT studies of isolated phthalates were carried out. In our study, isolated ligands were explored as potent antidiabetic as well as antioxidant agents as they exhibited good binding affinity (in in vitro and in silico experiments) against all selected protein targets. Compounds HR1–HR5 showed that the binding affinity value ranged from −5.9 to −5.2 kcal/mol, −5.5 to −4.3 kcal/mol, and −5.0 to −4.1 kcal/mol for target proteins 1HNY , 2I3Y , and 5O40 , respectively. Among all isolated phthalates, HR5 can be a lead compound as it showed the best binding affinity with human pancreatic α-amylase (Δ G = −5.9 kcal/mol) and displayed a minimum inhibition concentration (IC 50 ) of 11.69 μM among all phthalates. Compound HR1 was the best docked and scored compound for inhibiting glutathione peroxidase; however, HR2 possessed the lowest binding score of −5.0 kcal/mol, thus indicating the highest potential among isolated phthalates for inhibiting the superoxide dismutase. Furthermore, the top-ranked docked ligand–protein complex for each protein was assessed for stability of protein and complex mobility by molecular dynamics simulation using the IMOD server.

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“…The Hibiscus rosa sinensis, a highly potential, functional and valuable medicinal plant, has been reported in the ancient medicinal literature with beneficial effects in various disorders of humans 1 . Hibiscus rosa sinensis flowers are reported to contain quercetin, anthocyanins, flavonoids, cyclopeptide alkaloid and vitamins 2 .…”

Section: Introductionmentioning

confidence: 99%

Nutritional Assessment of Hibiscus Rosa Sinensis Flower, Formulation and Popularization of Hibiscus Flower Based Products

Sheeba¹,

Niveditha²

2018

FoodSci: Indian Journal of Research in Food Science and Nutrition

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Medicinal plants have been used in virtually all cultures as a source of medicine, since times immemorial. Hibiscus rosa sinensis Linn. (Family Malvaceae) is a plant which is widely distributed throughout the world. Pharmacological studies showed that flowers of H. rosa sinensis have numerous actions including antibacterial, wound healing, antidepressant, cardiac and antioxidant effects. This study aimed to estimate the nutritional value, phytochemical and physicochemical properties and microbial counts of hibiscus flowers (both fresh and dry). The result showed that the nutrient contents of hibiscus dry powder was higher than the hibiscus syrup. The chemical constituents present in the methanol and 50% aqueous-alcoholic extracts of fresh and dried hibiscus flower were alkaloids, glycosides, carbohydrates, phytosterols, polyphenols, tannins, saponins, flavonoids and proteins and amino acids and the constituents steroids, terpenoids and triterpenoids were absent. The physico-chemical parameters like total ash, acid insoluble ash, water soluble ash and sulphated ash were found to be high in dried flowers than fresh flowers. The bacterial count of hibiscus flower powder indicates that the sample stored in the ziplock polypack was minimum than in the plastic container and the yeast and mould count indicates that the sample stored in the plastic container was minimum than in the ziplock polypack. The hibiscus syrup and powder based products were also developed to create nutritional awareness among the adolescent girls.

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Potential Antibacterial Activity of Hibiscus rosasinensis Linn Flowers Extracts

Cited by 5 publications

References 9 publications

Effects of polyphenol‐rich traditional herbal teas on obesity and oxidative stress in rats fed a high‐fat–sugar diet

Effects of polyphenol‐rich traditional herbal teas on obesity and oxidative stress in rats fed a high‐fat–sugar diet

Plant-Based Bioactive Phthalates Derived fromHibiscus rosa-sinensis: As In Vitro and In Silico Enzyme Inhibition

Nutritional Assessment of Hibiscus Rosa Sinensis Flower, Formulation and Popularization of Hibiscus Flower Based Products

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