Potential Antioxidant and Anti-Proliferative Activities of Biologically Active Marine Algae Extracts

Kumosani, Taha A.; Balamash, Khadijah S.; Mohamed, Youssri; Baothman, Othman A.; Zeyadi, Mustafa; Yaghmoor, Soonham; Alyahiby, Areej; AL-Rasheed, Rana; Alturkistani, Wafa; Alghamdi, Tahani; Al-Zahrani, Maryam H.; Moselhy, Said S

doi:10.9734/jpri/2017/38089

Cited by 6 publications

(2 citation statements)

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“…The microalgae including Amphora, could be a source of a diverse class of bioactive compounds, especially the carotenoids (canthaxanthin and astaxanthin), polyunsaturated fatty acids, sulfated polysaccharides, β-glucans, and vitamins E and C, which are well-documented as bioactive compounds (Lee et al, 2009;El-Sayed et al, 2018). In addition, many researchers are interested in finding any natural antioxidants having safety and effectiveness, which can be substituted for current and commercial synthetic antioxidants (Taghvaei and Jafari, 2015;Kumosani et al, 2017;Glodde et al, 2018). Benthic diatoms as microalgae were considered as natural antioxidants (Lee et al, 2008;El-Sayed et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Significance Assessment of Amphora coffeaeformis in Arsenic-Induced Hemato- Biochemical Alterations of African Catfish (Clarias gariepinus)

et al. 2020

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Heavy metals have different adverse impacts on different life stages of fish species with attempts to use natural antioxidants to counteract their effects. So, the present study investigated the potential protective effects of Amphora coffeaeformis extract against arsenic-induced hemato-biochemical alterations in African catfish, Clarias gariepinus. The fish exposed to sub-lethal concentrations of arsenic; 19.2 and 38.3 mg/L (1/8 and 1/4 of 96h-LC 50 value, 153.17 mg/L) for 15 days. The main effect of arsenic was recorded in some blood parameters such as RBC's count, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, and white blood cells. As for biochemical parameters, the main effect of arsenic was significant for alkaline phosphatase, glucose, uric acid, creatinine, albumin, globulin, and albumin/globulin. Also, the residue of arsenic in fish muscles showed significant effects. The majority of these arsenic-induced parameters were improved with dietary supplements of the diatom A. coffeaeformis. So, Amphora extract can be used as detoxification factor on fishes induced by arsenic due to its biologically active components providing protections like antioxidant, antiviral, antibacterial, and anti-inflammatory. Besides, they have excellent contents of proteins and carbohydrates which are supposed to enhance the effect of these compounds.

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Section: Introductionmentioning

confidence: 99%

Significance Assessment of Amphora coffeaeformis in Arsenic-Induced Hemato- Biochemical Alterations of African Catfish (Clarias gariepinus)

et al. 2020

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“…Microscopic algae, including Amphora, can be a wellspring of an assortment of bioactive substances, particularly carotenoids, fats, carbohydrates, and vitamins, which are all around recorded as naturally bioactive compounds [23,24]. What's more, numerous scientists are keen on finding any successful normal antioxidants, which can be supplanted by manufactured antioxidants [25,26].…”

Section: Introductionmentioning

confidence: 99%

Amphora Coffeaeformis Modulate the Histopathological and Histochemical Disruption in Kidney and Gills of Clarias Gariepinus Intoxicated by Arsenic

2020

Assiut University Journal of Multidisciplinary Scientific Resea

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The arrival of pollutants such as heavy metals to the aquatic medium is known to affect such a domain and on its living life forms with endeavors to utilize the antioxidant agents to balance their effects. The present investigation explored the potential defensive impacts of Amphora coffeaeformis against arsenic-induced histopathology and histochemical adjustments in African catfish (Clarias gariepinus). Fish were exposed to sub-lethal doses of arsenic as 19.2 and 38.3 mg/l for 15 days. Kidneys of arsenic-exposed fish displayed tubular edema and necrosis, hematopoietic degeneration, melanomacrophage aggregates, Bowman's capsule edema and glomerulus shrinkage while gills of arsenic-exposed fish revealed lamellar rupture, lamellar aneurysm, edema, epithelial hypertrophy and mucous cell hyperplasia. PAS response revealed consumption in the carbohydrate materials in the kidney and gills in the arsenic group in contrast with control. The changes induced after arsenic-exposure was improved in fish fed amphora because of their naturally active components that can be utilized as antioxidant, antiviral, antibacterial, and anti-inflammatory for detoxification process.

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Screening of the bioactive compounds in Amphora coffeaeformis extract and evaluating its protective effects against deltamethrin toxicity in rats

Hassan

El-Sayed

Abdel-Wahhab

2020

Environ Sci Pollut Res

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Potential Antioxidant and Anti-Proliferative Activities of Biologically Active Marine Algae Extracts

Cited by 6 publications

References 0 publications

Significance Assessment of Amphora coffeaeformis in Arsenic-Induced Hemato- Biochemical Alterations of African Catfish (Clarias gariepinus)

Significance Assessment of Amphora coffeaeformis in Arsenic-Induced Hemato- Biochemical Alterations of African Catfish (Clarias gariepinus)

Amphora Coffeaeformis Modulate the Histopathological and Histochemical Disruption in Kidney and Gills of Clarias Gariepinus Intoxicated by Arsenic

Screening of the bioactive compounds in Amphora coffeaeformis extract and evaluating its protective effects against deltamethrin toxicity in rats

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