Potential biomarkers of emotional stress induced neurodegeneration

Abstract

Mental health is a matter of great significance and interest both socially and scientifically. The present review aims to provide an informative platform about the classical biomarkers available to identify and diagnose the neurodegeneration induced by emotional stress and depression. Present article provides an expert comprehensive overview of the universally accepted markers and their mechanism of action involved in emotional stress assessment and its management. This envisioned piece of work emphasize on the incorporation of clinical markers in classical psychiatry experiments will make the information more significant, reliable and universally accepted. The information summaries in the article will facilitates the researchers of clinical psychiatry, neuropharmacology and neuropsychiatry in management of depressive disorders along with the identification of possible neurodegenerative association.

An Evaluation of Speech-Based Recognition of Emotional and Physiological Markers of Stress

“…From this literature overview, it is clear that there is missing analysis in the literature, and need to explore more deeply the utility of markers of stress e. g., cortisol, in a machine learning paradigm. Computational understanding of cortisol is particularly meaningful, as it is known that, sustained levels of stress are substantial contributors to neurodegeneration (Zafar, 2020), with biological markers of this including fluctuations in neurotransmitters, e. g., dopamine or serotonin, and levels of stress hormones including cortisol, with Zafar (2020). More specifically, in Saitis and Kalimeri (2018) the authors use related bio-markers to automatically detect environments that are stressful for visually impaired persons which might help to improve accessibility within public spaces.…”

“…Understanding how stress manifests in the human body has several meaningful use-cases, from improving safety during driving (Bianco et al, 2019) to early intervention of neurodegeneration (Zafar, 2020). Stress levels are globally on the rise, primarily due to the increased pressure from work and personal lifestyles (Sharma et al, 2021).…”

Monoamine Oxidase as a Potential Biomarker of the Efficacy of Treatment of Mental Disorders

“…6 2021 ney damage, and others. However, no biomarkers for the application in psychiatry have been found so far [4,5].…”