Potential distributions and neural excitation patterns in a rotationally symmetric model of the electrically stimulated cochlea

Frijns, Johan H. M.; Snoo, Sander L. de; Schoonhoven, Ruurd

doi:10.1016/0378-5955(95)00090-q

Cited by 167 publications

(136 citation statements)

References 28 publications

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“…Bierer and Middlebrooks (2002) reported that increases in the spatial separation between bands of a modified Nucleus electrode led to ''a slight increase'' in the width of cortical images. Frijns et al (1996) modeled the effects of longitudinally oriented electrodes as well as those oriented radially. They found that longitudinal orientation had little effect on threshold but a modest effect on selectivity.…”

Section: Discussionmentioning

confidence: 99%

“…The approaches used in these studies range from saline tank/resistive network models of voltage distributions within the cochlea (Strelioff 1973;Black and Clark 1980;Black et al 1981Black et al , 1983O'Leary et al 1985;Girizon 1987;Ifukbe and White 1987;Kasper et al 1991;Suesserman and Spelman 1993;Jolly et al 1996;Kral et al 1998) to 2D and 3D computer simulations of intracochlear stimulation. These computer simulations attempt to model in vivo spatial excitation patterns produced by single electrodes in the spiral of the auditory nerve array (Finley 1989;Finley et al 1987Finley et al , 1990Frijns et al 1994Frijns et al , 1995Frijns et al , 1996Rattay et al 2001a,b). Some of these models predict highly restricted distributions of intracochlear current and subsequent patterns of auditory nerve activation (e.g., Frijns et al 1995Frijns et al , 1996Finley et al 1990;Rattay et al 2001b), especially when the electrodes are activated as intracochlear bipolar pairs or tripolar sets.…”

Section: Modeling Studiesmentioning

confidence: 99%

“…These computer simulations attempt to model in vivo spatial excitation patterns produced by single electrodes in the spiral of the auditory nerve array (Finley 1989;Finley et al 1987Finley et al , 1990Frijns et al 1994Frijns et al , 1995Frijns et al , 1996Rattay et al 2001a,b). Some of these models predict highly restricted distributions of intracochlear current and subsequent patterns of auditory nerve activation (e.g., Frijns et al 1995Frijns et al , 1996Finley et al 1990;Rattay et al 2001b), especially when the electrodes are activated as intracochlear bipolar pairs or tripolar sets. However, other models predict broad, complicated patterns of current spread in many activation modes including bipolar stimulation (Jolly et al 1996;Ifukube and White 1987;Black et al 1981).…”

Section: Modeling Studiesmentioning

confidence: 99%

“…1999;Bierer and Middlebrooks 2002;Middlebrooks and Bierer 2002), and theoretical modeling studies (Finley 1989;Finley et al 1987Finley et al , 1990Frijns et al 1994Frijns et al , 1995Frijns et al , 1996Rattay et al 2001a,b). Previous studies have been limited by a number of technical problems.…”

Section: Introductionmentioning

confidence: 99%

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Topographic Spread of Inferior Colliculus Activation in Response to Acoustic and Intracochlear Electric Stimulation

Snyder

Bierer

Middlebrooks

2004

JARO

140

158

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The design of contemporary multichannel cochlear implants is predicated on the presumption that they activate multiple independent sectors of the auditory nerve array. The independence of these channels, however, is limited by the spread of activation from each intracochlear electrode across the auditory nerve array. In this study, we evaluated factors that influence intracochlear spread of activation using two types of intracochlear electrodes: (1) a clinical-type device consisting of a linear series of ring contacts positioned along a silicon elastomer carrier, and (2) a pair of visually placed (VP) ball electrodes that could be positioned independently relative to particular intracochlear structures, e.g., the spiral ganglion. Activation spread was estimated by recording multineuronal evoked activity along the cochleotopic axis of the central nucleus of the inferior colliculus (ICC). This activity was recorded using silicon-based singleshank, 16-site recording probes, which were fixed within the ICC at a depth defined by responses to acoustic tones. After deafening, electric stimuli consisting of single biphasic electric pulses were presented with each electrode type in various stimulation configurations (monopolar, bipolar, tripolar) and/or various electrode orientations (radial, off-radial, longitudinal). The results indicate that monopolar (MP) stimulation with either electrode type produced widepread excitation across the ICC. Bipolar (BP) stimulation with banded pairs of electrodes oriented longitudinally produced activation that was somewhat less broad than MP stimulation, and tripolar (TP) stimulation produced activation that was more restricted than MP or BP stimulation. Bipolar stimulation with radially oriented pairs of VP ball electrodes produced the most restricted activation. The activity patterns evoked by radial VP balls were comparable to those produced by pure tones in normal-hearing animals. Variations in distance between radially oriented VP balls had little effect on activation spread, although increases in interelectrode spacing tended to reduce thresholds. Bipolar stimulation with longitudinally oriented VP electrodes produced broad activation that tended to broaden as the separation between electrodes increased.

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Section: Discussionmentioning

confidence: 99%

Section: Modeling Studiesmentioning

confidence: 99%

Section: Modeling Studiesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Topographic Spread of Inferior Colliculus Activation in Response to Acoustic and Intracochlear Electric Stimulation

Snyder

Bierer

Middlebrooks

2004

JARO

140

158

View full text Add to dashboard Cite

show abstract

“…Animal studies will be invaluable in understanding how electrical and acoustic signals interact in the cochlea and central nervous system and how to minimize perceptual distortions resulting from these interactions through changes in signal processing and/or electrode array design (von Ilberg et al, 1999;Nourski et al, 2005;Vollmer, 2006, personal communication). Based on computer modeling, this group of patients may perform best using an intracochlear electrode array specifically designed to selectively activate peripheral dendrites within the osseous spiral lamina (OSL) rather than spiral ganglion cells in the modiolus (Frijns et al, 1995;Frijns et al, 1996).…”

Section: Future Directionsmentioning

confidence: 99%