Potential of Evening Primrose, Borage, Black Currant, and Fungal Oils in Human Health

Barre, Douglas Edward

doi:10.1159/000046706

Cited by 83 publications

(47 citation statements)

References 80 publications

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“…Borage (B. officinalis) oil has been used for the treatment of depression, inflammation, fevers, and coughs, although these uses have not been empirically tested. GLA, a polyunsaturated fatty acid, is the ingredient of borage seed oil that is reported to be responsible for its beneficial, specifically anti-inflammatory health effects [7,8]. Borage oil products typically contain 20-27% GLA [7].…”

Section: Discussionmentioning

confidence: 99%

“…GLA is thought to exert its therapeutic effect in rheumatologic and dermatologic conditions by inhibiting leukotriene synthesis, resulting in anti-inflammatory and anti-thrombotic effects [7,8]. Borage seed oil has been estimated to contain the highest amounts of GLA: 23% compared to black currant seed oil or evening primrose oil, both of which are also well known herbal supplement sources of GLA [7].…”

Section: Discussionmentioning

confidence: 99%

“…Borage seed oil has been estimated to contain the highest amounts of GLA: 23% compared to black currant seed oil or evening primrose oil, both of which are also well known herbal supplement sources of GLA [7]. Borage seed oil also contains high concentrations (up to 35-38%) of LA, another omega-6 fatty acid, and a precursor to GLA in normal fatty acid metabolism.…”

Section: Discussionmentioning

confidence: 99%

“…Borage seed oil is derived from the seeds of the borage plant (Borago officinalis). Borage seed oil, which contains gamma-linolenic acid (GLA) and linoleic acid (LA), is popular because of its use medicinally as an anti-inflammatory for treating arthritis, as well as for the treatment of certain skin conditions (e.g., atopic dermatitis), menopause-related symptoms and diabetic neuropathy [7]. We report a case of status epilepticus temporally associated with the use of borage seed oil.…”

Section: Introductionmentioning

confidence: 99%

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Status Epilepticus Associated with Borage Oil Ingestion

et al. 2011

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The use of herbal and complementary medicine is common. Many herbal products are known to produce serious adverse effects. Borage oil is derived from the seeds of the borage plant (Borago officinalis) an abundant source of gamma-linolenic acid (GLA), and Borage oil has been promoted as a treatment for rheumatoid arthritis, atopic dermatitis, diabetic neuropathy, and menopause-related symptoms. We report a case of status epilepticus in a patient who consumed borage oil for one week.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Status Epilepticus Associated with Borage Oil Ingestion

et al. 2011

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“…microbial, evening primrose, borage and black currant) are associated with their potential especially in human medicine (Barre, 2001), however, few studies have been available on effects of GLA on the rumen lipid metabolism. In our first experiment, the T and the D affected the daily outputs of fatty acids (FA) in all LH+WB diets (Table 6).…”

Section: Fatty Acids and Biohydrogenationmentioning

confidence: 99%

Prefermented cereals containing fungal gamma-linolenic acid and their effect on rumen metabolism in vitro

Laho¹,

Váradyová²,

Mihaliková³

et al. 2011

CZECH J ANIM SCI

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ABSTRACT:The application of Thamnidium elegans fungal strain CCF 1456 (TE) for effective utilization of various agroindustrial materials creates new perspectives for animal cereal diets enriched with microbial γ-linolenic acid (GLA). Diets consisting of lucerne hay (LH) plus prefermented cereals (wheat bran/spent malt grains, WB+TE or WB+TE enriched with sunflower oil, WB+SO+TE in the first experiment and ground maize grains, GC+TE in the second experiment) were used in the artificial rumen. We examined their effect on the rumen fermentation pattern and lipid metabolism. The diet affected the results of degradability of dry matter, organic matter, neutral detergent fibre and acid detergent fibre of LH+WB diets (P < 0.05 and P < 0.01). The GLA daily output of prefermented diet substrates LH+WB+TE and LH+WB+SO+TE, or LH+GC+TE was higher compared to the non-prefermented LH+WB or LH+GC, respectively (P < 0.05 and P < 0.01). Daily outputs of trans11 oleic (TVA) of the LH+GC+TE diet were higher versus the non-prefermented LH+GC (P < 0.01). The biohydrogenation of fatty acids (C18:1 cis9 oleic, C18:2 linoleic, C18:3n-3 alpha-linolenic, C18:3n-6 GLA and total FA) of prefermented cereal diets was not influenced. Cereal diets containing microbial GLA might positively enhance GLA daily outputs in the RUSITEC effluent, but they are not effective enough to decrease the biohydrogenation of unsaturated fatty acids.

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Borage ( Borago officinalis L.)

Barceloux

2008

Medical Toxicology of Natural Substances

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The large, deep green, leaves of common borage are covered with white, stiff, prickly hairs, and occasionally the leaves of borage may be confused with the large, fussy, deep green leaves of foxglove. Misidentifi cation of foxglove for borage resulted in digitoxin poisoning after the patient ingested a brewed tea from the misidentifi ed foxglove leaves. 1 Physical Description: This hairy, annual herb grows up to 2 -3 ft ( ∼ 60 -90 cm) in height. The leaves are alternate, wrinkled, oval, and pointed with dimensions of about 1.5 by 3 in ( ∼ 4 cm by 8 cm). Bright blue to pink, star -shaped fl owers appear in loose racemes during the summer. Borage has a salty fl avor with an aroma of cucumbers. Distribution and Ecology: This plant inhabits wide areas of the west coast and the northern and northeastern states of the United States, as well as southern Europe. Although this plant is native to Syria, common borage has naturalized in the warmer parts of central, eastern, and western Europe. The common name, bee plant, is derived from the use of this plant as an attractant for honeybees.

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Potential of Evening Primrose, Borage, Black Currant, and Fungal Oils in Human Health

Cited by 83 publications

References 80 publications

Status Epilepticus Associated with Borage Oil Ingestion

Status Epilepticus Associated with Borage Oil Ingestion

Prefermented cereals containing fungal gamma-linolenic acid and their effect on rumen metabolism in vitro

Borage ( Borago officinalis L.)

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