Potential use of curcumin loaded carboxymethylated guar gum grafted gelatin film for biomedical applications

Carboxymethyl guar gum nanoparticles for drug delivery applications: Preparation and preliminary in-vitro investigations

“…The formation of CMGG was confirmed by 1 H and 13 C-NMR results (Figure 2), which were in good agreement, with other studies (Manna et al, 2015). The 1 H-NMR spectrum showed new proton peaks at 3.77, 3.95 and 4.22 ppm, attributed to the methylene protons from the carboxyl group, in addition to the anomeric (4.70 and 5.03 ppm) and sugar protons (3.57 and 4.13 ppm) found in the raw GG.…”

Non-thermal plasma assisted surface nano-textured carboxymethyl guar gum/chitosan hydrogels for biomedical applications

“…This reduction in crystallinity might be attributed to the presence of hydrogen bonds, which might have disrupted the ordered polymer chains of GG and thereby reducing the crystallinity. 10,19 3.1.3. SEM analyses.…”

“…Native GG exhibits peaks at d 4.7 and d 3.5-4.0 ppm associated with anomeric protons and sugar protons respectively. 19 The CMGG spectrum revealed the appearance of new proton peaks at d 3.75, 3.8 and 3.9 ppm ascribed to the Scheme 1 Carboxymethylation of guar gum. 11,19 Thus, the proton NMR results conrm the carboxymethylation reaction.…”

“…[10][11][12][13][14] Carboxymethylated guar gum (CMGG) has been assimilated with myriad polymers and formulated into nanoparticles, microspheres, microparticles and hydrogels among others and employed for biomedical applications. [14][15][16][17][18][19][20][21][22] Chitosan (CS) is a natural cationic pH-responsive polymer which needs no introduction. CS is endowed with inimitable features like biodegradability, biocompatibility, non-toxicity and thus nds promising applications in pharmaceutics.…”

Evolutionary approaches in protein engineering towards biomaterial construction

“…Also, gelatin lms graed with carboxy methylated guar gum incorporated with a natural antimicrobial compound curcumin serves as an excellent wound healing biomaterial. 61 Wound healing by collagen, chitosan or silk proteins sericin/broin have also been enhanced by incorporating anti-inammatories, antiseptics, antibiotics, nanoparticles and other bioactive agents. 62,63 Use of plasma modied collagen is yet another new approach towards wound healing 64 mainly in diabetic and immuno-compromised patients.…”