Potential use of Sambucus nigra ointments for skin treatment in ethnomedicine in Republic of North Macedonia

Antibacterial and Antioxidant Activity of Cosmetic Creams With Extracts of Dry Flowers and Fruits of Sambucus Nigra L. - Use of Sambucus Nigra L. As a Non-Traditional Chemical Preservative

“…The high antioxidant capacity and amount of total polyphenolic compounds of the ethanolic S. nigra extracts used by us have been established and commented on in our other publications [27] and confirmed by other authors [8,13,14,19]. Phenolic extracts contain various bioactive compounds (n-rutin; quercetin 3-O-rutinoside) that can potentiate antimicrobial activity as well as add different biological activities to cosmetic products, increasing their potential as natural preservatives over synthetic ones in cosmetics [28,29].…”

“…Due to the high bioactivity (anthocyanins) in S. nigra species, different coloration, high stability, resistance to temperature changes, moisture, and light, due to the stable pH of the target S. nigra matrix. In addition, the processing conditions also did not change the pH values and could be a beneficial technological solution for S. nigra use in skin treatment [19].…”