Potential Utilization of Green Tide-Forming Macroalgae from Patos Lagoon, Rio Grande-RS, Brazil

Coelho, Michele Silveira; Menezes, Bruna da Silva; Meza, Silvia Letícia Rivero; Gianasi, Bruno L.; Salas-Mellado, Myriam de las Mercedes; Copertino, Margareth; Souza, Michele da Rosa Andrade Zimmermann de

doi:10.1080/10498850.2015.1012688

Cited by 6 publications

(1 citation statement)

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“…In this study, polysaccharides from the green tide seaweed, C. isthmocladum, were studied to derive more ideas for the optimal utilization of this seaweed to efficiently solve the growing problem of global pollution [20].…”

Section: Introductionmentioning

confidence: 99%

Structure and Anticoagulant Activity of a Galactofuranose-Containing Sulfated Polysaccharide from the Green Seaweed, Codium isthmocladum

Bai

Zhang

et al. 2022

Molecules

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A water-soluble sulfated polysaccharide, F2-1, was obtained from the marine green alga, Codium isthmocladum, using ion-exchange and size-exclusion chromatography. Structure analysis showed that the F2-1 was a sulfated arabinan comprising Ara, Rha, Man, Gal, and Xyl with an 18% sulfate content and a molecular weight of 100 kDa. Methylation analysis combined with desulfation, GC-MS, IR, and NMR spectroscopy showed that the backbone of F2-1 was →4)-β-L-Arap(1→ residue. Its 2-O and/or 3-O positions showed sulfate modification; additionally, the 2-O or 3-O position showed branch points. The side chains were composed of →5)-β-D-Galf, (1→2,6)-β-D-Galf(1→, (1→2)-β-L-Rhap4S, →4)-α-D-Glcp(1→, and terminal α-D-Galp(1→ and β-D-Xylp(1→. Polysaccharides containing β-D-galactofuranose are rarely found in seaweed. F2-1 exhibited significant anticoagulant activity in vitro. Our findings suggested that the green-tide alga, Codium isthmocladum, can be considered as a useful resource for bioactive polysaccharides.

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Section: Introductionmentioning

confidence: 99%