Potentialities of Platelet-Rich Plasma Use in Treatment of Knee Osteoarthrosis

Khalimov, E. V.; Savel’ev, S. N; Khalimov, A. E.; Nuriev, R. F.; Ochkurenko, A. A

doi:10.17816/vto201623323-27

N.N. Priorov Journal of Traumatology and Orthopedics

2016

DOI: 10.17816/vto201623323-27

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Potentialities of Platelet-Rich Plasma Use in Treatment of Knee Osteoarthrosis

E. V. Khalimov¹,

S. N Savel’ev²,

A. E. Khalimov³

et al.

Abstract: Results of the use of platelet-rich plasma (PRP) in patients with knee osteoarthrosis are presented. The study included 86 patients with I-III degree of knee osteoarthrosis (141 knee joints). All patients received 2 intraarticular injections of PRP with 14 days interval. Pain severity was assessed by visual analog scale in 6 and 12 months after treatment. The most significant positive dynamics was observed in patients with II degree - 50.6±2.32, 16.3±2.31 ( р

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Treatment of horizontal dissection of the knee menisci with platelet-rich plasma (PRP). Literature review and analysis of own data

Lisitsyn

Atlukhanov²,

Zaremuk

et al. 2021

N.N. Priorov Journal of Traumatology and Orthopedics

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BACKGROUND: Treatment of damage to the inner layer of the meniscus of the knee joint that does not extend to the articular surface remains an open question. Subsequently, these injuries can cause a complete rupture of the meniscus that already requires surgical treatment. Existing methods of treatment at this stage of meniscus injury have not shown their effectiveness. AIM: Study the effect of platelet-rich plasma (PRP) on meniscus regeneration. MATERIALS AND METHODS: The analysis of the 15 patients treatment results with the PRP method, which effectively stimulates regenerative processes, was carried out. The effectiveness of the method was assessed using the following evaluation scales: visual analog scale (VAS), Lequesne scale, WOMAC index (Western Ontario and McMaster Universities Osteoarthritis Index), Lysholm scale, KSS scale (Knee Society Score) and magnetic resonance imaging (MRI). RESULTS: According to the results of MRI performed after 6 months, there was no progression of meniscus damage after PRP therapy by all parameters. CONCLUSION: The study showed an improvement in all rating scales. In addition, according to MRI data, after 6 months there was no progression of the degenerative process in the menisci. The presented method can be the first step in the treatment of this pathology.

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Treatment of horizontal dissection of the knee menisci with platelet-rich plasma (PRP). Literature review and analysis of own data

Lisitsyn

Atlukhanov²,

Zaremuk

et al. 2021

N.N. Priorov Journal of Traumatology and Orthopedics

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Application of autoplasma enriched with thrombocytes in the comprehensive treatment of acute pancreatitis

Mikhailov,

Khalimov,

Remnyakov

2024

VESTNIK KHIRURGII IMENI I.I.GREKOVA

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The OBJECTIVE was to assess the proposed treatment method for patients with acute pancreatitis in the 1 A phase of the disease’s development.METHODS AND MATERIALS. The data from the treatment of patients in the surgical departments of the City Clinical Hospital ¹ 6 in Izhevsk (Clinic of the Department of General Surgery, Izhevsk State Medical Academy) were ana lyzed. Two groups of patients with acute pancreatitis in the 1A phase of the disease development were formed. In the observation group, in addition to the basic treatment, autoplasmic thrombocyte concentrate was administered into the round ligament of the liver. The dynamics of the process and treatment outcomes were assessed based on the criteria scale of primary express assessment of acute pancreatitis severity by the St. Petersburg Research Institute named after I. I. Dzhanelidze (2006), leukocyte index of intoxication by V. K. Ostrovsky (2018), and the J. Ranson scale (1974).RESULTS. The use of autoplasmic thrombocyte concentrate in the observation group allows reducing the number of minimally invasive interventions to 17.7 %, or by 42.1 %, and the number of laparotomies to 5, or by 54.5 %, compared to the comparison group, avoiding fatal outcomes.CONCLUSION. The use of autoplasmic thrombocyte concentrate in the comprehensive treatment of patients with acute pancreatitis in the 1 A phase of development and its targeted delivery through the round ligament of the liver allows preventing lethality, reducing the number of complications of acute pancreatitis requiring surgical intervention.

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Potentialities of Platelet-Rich Plasma Use in Treatment of Knee Osteoarthrosis

Cited by 2 publications

References 11 publications

Treatment of horizontal dissection of the knee menisci with platelet-rich plasma (PRP). Literature review and analysis of own data

Treatment of horizontal dissection of the knee menisci with platelet-rich plasma (PRP). Literature review and analysis of own data

Application of autoplasma enriched with thrombocytes in the comprehensive treatment of acute pancreatitis

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