Powassan Virus: Field Investigations during the Summer of 1963 *

McLean, D. M.; Vos, Antoon de; Quantz, E. J.

doi:10.4269/ajtmh.1964.13.747

Cited by 34 publications

(32 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…From these reports, it appears that lineage I Powassan encephalitis is characterized by respiratory distress, fever, vomiting, convulsions, and occasionally paralysis 17,19. Studies in the northern Ontario region of Canada show an antibody prevalence rate of as much as 3.2%, indicating that infection does not always cause severe disease 22. In a phylogenetic study of Powassan-related viruses of North America, a lineage II strain (ON97) was reportedly isolated from human brain tissue 2.…”

Section: Discussionmentioning

confidence: 99%

Fatal Case of Deer Tick Virus Encephalitis

et al. 2009

View full text Add to dashboard Cite

SUMMARY Deer tick virus is related to Powassan virus, a tickborne encephalitis virus. A 62-year-old man presented with a meningoencephalitis syndrome and eventually died. Analyses of tissue samples obtained during surgery and at autopsy revealed a widespread necrotizing meningoencephalitis. Nucleic acid was extracted from formalin-fixed tissue, and the presence of deer tick virus was verified on a flavivirus-specific polymerase-chain-reaction (PCR) assay, followed by sequence confirmation. Immunohistochemical analysis with antisera specific for deer tick virus identified numerous immunoreactive neurons, with prominent involvement of large neurons in the brain stem, cerebellum, basal ganglia, thalamus, and spinal cord. This case demonstrates that deer tick virus can be a cause of fatal encephalitis.

show abstract

Section: Discussionmentioning

confidence: 99%

Fatal Case of Deer Tick Virus Encephalitis

et al. 2009

View full text Add to dashboard Cite

show abstract

“…Ixodes cookei Packard, 1869 is a vector of Powassan virus, a cause of human encephalitis in northern Ontario, Canada (Mclean et al 1964;Chernesky 1969). The biology of this ixodid tick has not been studied previously.…”

Section: Introductionmentioning

confidence: 98%

Biology of Ixodes cookei Packard (Ixodidae) of groundhogs (Marmota monax Erxleben)

Ko¹

1972

Can. J. Zool.

View full text Add to dashboard Cite

KO, R. C. 1972. Biology of Ixodes cookei Packard (Ixodidae) of groundhogs (Marmota monax Erxleben).Can. J. Zool. 50: 433436. Observations were made on the biology of the tick under natural conditions in southern Ontario and in the laboratory at 30C and 90-95% relative humidity. Twenty-nine percent of 569 groundhogs examined from March to September during 1969 and 1970 were infested with I. cookei. Four hundred and forty-four I. cookei were collected; most females were recovered in May and larvae in August. In the laboratory the life cycle of the tick was completed in about 3 months. Most females began to lay eggs 4 days after feeding. Eggs hatched in about 3 weeks. Larvae molted about 3 weeks after feeding and nymphs in about 4 weeks. KO, R. C, 1972. Biology of Ixodes cookei Packard (Ixodidae) of groundhogs (Mavmota monax Erxleben). Can. J. Zool. 50: 433-436. Des Ixodes cookei ont kt6 gardBs dans des conditions naturelles dans le sud de I'Ontario, et en laboratoire a 30°C et a 90-95% humidit6 relative. De 569 marmottes exarninks entre mars et septembre en 1969 et 1970,29% Btaient parasitkes par I. cookei. Quatre cent quarante-quatre acariens ont kt6 rkoltks, la plupart des femeUes ayant kt6 capturks en mai et les larves en ao8t. En laboratoire, le cycle vital de la tique est d'environ 3 mois. La plupart des femelles commencent a pondre 4 jours aprks avoir mangk. Les oeufs Bclosent au bout de 3 semaines environ. Les larves muent quelques 3 semaines apres avoir mangk, alors que les nymphes mettent peu prks 4 semaines a se mktamorphoser.

show abstract

“…Antibodies to Powassan have been detected in small mammals (ground squirrels and hares) in serological surveys in British Columbia (McLean et al , 1970 and Alberta (Hoff et al 1970;Zarnke and Yuill 1981), but attempts to isolate this virus from D. andersoni collected from some of these animals or from the environment have failed (McLean et al , 1970. Powassan virus has been isolated from D. andersoni collected in South Dakota (McLean and Quantz 1964;Keirans and Clifford 1983), Colorado (Thomas et al 1960) and California (Calisher 1994); thus, this agent may be potentially present in D. andersoni in Canada.…”

Section: A C D Bmentioning

confidence: 99%

The Biological Survey of Canada: A Personal History

Danks¹

2017

View full text Add to dashboard Cite

Powassan Virus: Field Investigations during the Summer of 1963 *

Cited by 34 publications

References 0 publications

Fatal Case of Deer Tick Virus Encephalitis

Fatal Case of Deer Tick Virus Encephalitis

Biology of Ixodes cookei Packard (Ixodidae) of groundhogs (Marmota monax Erxleben)

The Biological Survey of Canada: A Personal History

Contact Info

Product

Resources

About