Powdered diethylaminoethyl cellulose as biomass-derived support for phosphotungstic acid: new solid acidic catalyst for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones

Diethylaminoethyl cellulose (DEAE-C) between chromatography and synthetic applications

“…The catalyst could be easily recovered by simple filtration and reused several times with minor decreases in the reaction yields. 58 A simple, reliable, and rapid method based on modifying the cellulose surface by doping it with different percentages of lanthanum hydroxide [e.g., 1% La(OH) 3 -cellulose (LC), 5% La(OH) 3 -cellulose (LC2), and 10% La(OH) 3 -cellulose (LC3)] was proposed by Marwan and co-workers. This modified cellulose became a selective marker for detection of copper Cu(II) in aqueous medium (Figure 10).…”

2,3-Dihydroquinazolin-4(1H)-one as a privileged scaffold in drug design

“…On the other hand, solid acids used in reuxing EtOH lengthened the reaction time to 5-7 hours. 111,112 Montmorillonite K-10 is one of the most important smectites, a phyllosilicate mineral species, used as a catalyst in organic synthesis. It is a clay with both BrØnsted and Lewis acid sites, with a high cation-exchange capacity.…”

Hydroxyapatite nanoparticles (HAP NPs): a green and efficient heterogeneous catalyst for three-component one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives in aqueous media

“…12 In view of their widely increased application value, a number of classical methods for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones have been reported in the literature. [13][14][15] These methods include: (i) condensation of o-aminobenzamide with aldehydes or ketones using Lewis or Brønsted acids 16 (ii) reductive cyclization of o-nitrobenzamide/or o-azido-benzamide with aldehydes or ketones using SnCl 2 /or metallic samarium in the presence of iodine or SmI 2 16a,17 (iii) condensation of isatoic anhydride, primary amines or ammonium salts with aldehydes or ketones in the presence of p-toluenesulfonic acid (PTSA), 16b citric acid, 18 silica sulfuric acid (SSA), 19 silica-bonded N-propylsulfamic acid, 20 silica-bonded S-sulfonic acid, 21 MCM-41-SO 3 H, 22 ethylenediamine diacetate, 16g Ga(OTf) 3 , 23 KAl(SO 4 ) 2 Á12H 2 O, 24 Al(H 2 PO 4 ) 3 , 25 montmorillonite K-10, 26 heteropolyacids (HPAs), 27 powdered diethylaminoethyl cellulose as the biomass-derived support for phosphotungstic acid, 28 SrCl 3 Á6H 2 O, 29 molecular iodine, 30 magnetic Fe 3 O 4 , nanoindium oxide, Al/Al 2 O 3 nanoparticles, [31][32][33] or with the aid of ultrasound irradiation catalyzed by dodecylbenzenesulfonic acid 34 and microwaves in the presence of Amberlyst-15 35 or Cu-CNTs. 36 2,3-Dihydroquinazolin-4(1H)-one derivatives were previously prepared by multi-step reactions.…”