Power spectral analysis and cortical coupling of EEG for young and old normal adults

Dustman, Robert E.; LaMarche, Judith A.; Cohn, Nancy; Shearer, Donald E.; Talone, James M.

doi:10.1016/0197-4580(85)90049-1

Cited by 70 publications

(20 citation statements)

References 29 publications

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“…Large age-related changes are seen in EEG power during brain development (Basar, Yordanova, Kolev, & Basar-Eroglu, 1997; Dustman, Shearer, & Emmerson, 1993; Katada, Ozaki, Suzuki, & Suhara, 1981). Consistent with our observations in rats, in the present study, higher cortical power in the EEG has also been reported in human adolescents relative to adults (Dustman, LaMarche, Cohn, Shearer, & Talone, 1985; Dustman, Shearer, & Emmerson, 1999; Ehlers, Wall, Garcia-Andrade, & Phillips, 2001). …”

Section: Discussionsupporting

confidence: 93%

Developmental differences in EEG and sleep responses to acute ethanol administration and its withdrawal (hangover) in adolescent and adult Wistar rats

Ehlers

Desikan

Wills

2013

Alcohol

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Age-related differences in sensitivity to the acute effects of alcohol may play an important role in the increased risk for the development of alcoholism seen in teens that begin drinking at an early age. The present study evaluated the acute and protracted (hangover) effects of ethanol in adolescent (P33–P40) and adult (P100–P107) Wistar rats, using the cortical electroencephalogram (EEG). Six minutes of EEG was recorded during waking, 15 min after administration of 0, 1.5, or 3.0 g/kg ethanol, and for 3 h at 20 h post ethanol, during the rats’ next sleep cycle. Significantly higher overall frontal and parietal cortical power was seen in a wide range of EEG frequencies in adolescent rats as compared to adult rats in their waking EEG. Acute administration of ethanol did not produce differences between adolescents and adults on behavioral measures of acute intoxication. However, it did produce a significantly less intense acute EEG response to ethanol in the theta frequencies in parietal cortex in the adolescents as compared to the adults. At 20 h following acute ethanol administration, during the rats’ next sleep cycle, a decrease in slow-wave frequencies (1–4 Hz) was seen and the adolescent rats were found to display more reduction in the slow-wave frequencies than the adults did. The present study found that adolescent rats, as compared to adults, demonstrate low sensitivity to acute ethanol administration in the theta frequencies and more susceptibility to disruption of slow-wave sleep during hangover. These studies may lend support to the idea that these traits may contribute to increased risk for alcohol use disorders seen in adults who begin drinking in their early teenage years.

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Section: Discussionsupporting

confidence: 93%

Developmental differences in EEG and sleep responses to acute ethanol administration and its withdrawal (hangover) in adolescent and adult Wistar rats

Ehlers

Desikan

Wills

2013

Alcohol

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“…For studies that observe cortical coupling by means of measuring the coherence between signals from different electrode locations, the common observation is a higher synchronization for older compared to younger subjects (e.g., Dustman et al, 1985Dustman et al, , 1993. Such findings are in general consistent with the notions of functional dedifferentiation with advancing age due to declining neuromodulation (e.g., Li et al, 2005;Ba¨ckman et al, 2006) or a general loss of inhibitory connections Kinsbourne and Hicks, 1978. …”

Section: Aging-related Changes In Brain Structures and Electrophysiolmentioning

confidence: 79%

Cortical EEG correlates of successful memory encoding: Implications for lifespan comparisons

Werkle‐Bergner

Müller

et al. 2006

Neuroscience & Biobehavioral Reviews

123

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In the course of their lives, individuals experience a myriad of events. Some of them leave stable traces, and others fade away quickly. Recent advances in functional imaging methods allow researchers to contrast neuronal patterns of remembered against not remembered events at initial encoding. Research on young adults using functional magnetic resonance imaging (fMRI), intracranial, and standard electroencephalographic (EEG) recordings has identified differences between remembered and not remembered items in patterns of medio-temporal and prefrontal brain activity. However, little is known about the ways in which such neuronal patterns of successful encoding evolve across the lifespan as a function of maturation, senescence, and the accumulation of experience. Here, we first review empirical evidence on neuronal correlates of successful memory from middle childhood to old age. Based on the observation that associative and strategic components of episodic memory seem to follow different age gradients, we propose a conceptual framework for predicting age changes in neuronal patterns of successful encoding. r

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“…Under physiological conditions, the amount of slow-wave activity in the EEG is not increased in old age [2,5,12,13]. Instead, there may be a decrease in power in all frequency bands [14].…”

Section: Introductionmentioning

confidence: 99%

Short-Term Rivastigmine Treatment Reduces EEG Slow-Wave Power in Alzheimer Patients

Adler

Brassen²

2001

Neuropsychobiology

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The effects of a 5-day treatment with rivastigmine on the resting EEG power spectrum were studied in 15 mildly to moderately ill Alzheimer patients. In these patients, beta power was positively correlated with cognitive performance and negatively correlated with functional impairment. Rivastigmine produced a decrease in delta and theta power with no effect of hemisphere and electrode position. Delta power decrease reflects the cerebral cholinergic action of rivastigmine and may thus allow a quantitative assessment of its CNS effects.

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Power spectral analysis and cortical coupling of EEG for young and old normal adults

Cited by 70 publications

References 29 publications

Developmental differences in EEG and sleep responses to acute ethanol administration and its withdrawal (hangover) in adolescent and adult Wistar rats

Developmental differences in EEG and sleep responses to acute ethanol administration and its withdrawal (hangover) in adolescent and adult Wistar rats

Cortical EEG correlates of successful memory encoding: Implications for lifespan comparisons

Short-Term Rivastigmine Treatment Reduces EEG Slow-Wave Power in Alzheimer Patients

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