PP.06.11

Abstract

Results: 1766 patients were enrolled, and 1423 of them completed the first visit -641 from Ivanovo (mean age 52±9 years, 244 men), and 782 from Saratov (mean age 58 ± 12 years, 449 men). The data of the first visit were used for preliminary analysis. We found no seasonal or intraregional differences in 24-hour pulse wave velocity. At the same time, the values of both 24-hour brachial and aortic augmentation indices were higher in winter (-5.9% ± 2.0% vs. -13.1% ± 2.7%; 27.4% ± 1.3% vs. 22.5% ± 1.7%, respectively, p < 0.05). Conclusions:Despite some limitations of preliminary analyses, our results show the decrease of 24-hour arterial stiffness associated with higher temperature. 24hour oscillometric monitoring seems to be a promising method of arterial stiffness measurement. Further individual analysis of these data is needed.Objective: For use of indicators of Central aortic pressure (CAP) for the purpose of early diagnosis of preclinical atherosclerosis it is necessary to consider sexual features of the specified parameters. We investigated distinctions of indicators of the Central aortic haemodynamic between young men and girls.Design and method: Overall, 52 students from 19 to 23 years of age (25 boys and 27 girls) were recruited in this study according results of preventive medical exemanation. Investigation includes the BPLab®Vasotens Office device (Petr Telegin, Russia), which has passed quality ESH-2011 test. Waveforms were analyzed using the special automatic Vasotens® algorithm, which allows the calculation of central systolic (SYSao), diastolic (DIAao), mean (MBPao) and puls (PPao) blood pressure, central augmentation index (AIxao), amplification of the pulse pressure (PPA) and ejection duration (ED). We used BPStat software, version 05.00.04 (BPLab) to tabulate all the indices of every office measured wave form automatically. The data are presented as the median (25-75 percentile). An alpha level of 5% was considered to be statistically significant. The study was approved by the local ethics committee.

Vasera-screening of premature vascular aging and its correction in young persons: University Health Center experience

“…The instrumental angiological screening we used among young people is optimally suited for this purpose. These results show that it is no longer possible to limit the use of classical RF [7,8], as was done until recently when conducting youth screening. Predictive diagnostic advantages of vascular stiffness in comparison with other RF are due to its nature as a "tissue" biomarker in comparison with "circulating" biomarkers such as lipids, C-reactive protein, homocysteine, etc., the level of which constantly fluctuates in the human body [9].…”