Pp078-Mon Catheter-Related Complications in Home Parenteral Nutrition in Cancer Patients: A Prospective Study of Over 51,000 Catheter Days

Risk Factors for the Development of Catheter‐Related Bloodstream Infections in Patients Receiving Home Parenteral Nutrition

“…1,[3][4][5][6][7][8][9][10][11][12][13] In children, infection rates as high as 7 per 1000 days have been reported. 14 The important issue, however, is how this infection risk can be lowered.…”

Outcome of Pediatric Gastroenterology Outpatients With Fever and Central Line

“…[1][2][3] In well-appearing nonneutropenic febrile children with cancer and a CVC, studies have demonstrated the safety of outpatient management of fever, which includes the collection of blood cultures and administration of broad-spectrum, long-acting antibiotics through the CVC. 4,5 Children with high-risk features such as an ill appearance, hypoxia, or hypotension are admitted for ongoing treatment.…”

“…Literature on adult inpatients shows that the use of TPN is an independent risk factor for catheter-associated bloodstream infections [7][8][9] but this increased risk is not seen in adults using TPN at home. 1,10,11 Pediatric gastroenterology patients receiving TPN at home have central line-associated bloodstream infection (CLABSI) incidence rates of 1.4 to 7.0 per 1000 catheter days. [12][13][14][15][16] Comparing CLABSI risk across studies is difficult because this risk is heavily influenced by a variety of factors including underlying diagnosis, purpose of CVC, type of CVC, inpatient status, and age of patient.…”

Management of Home Parenteral Nutrition: A Prospective Multicenter Observational Study

“…This is probably due to the fact that patients with neurological disorders can mostly be treated with enteral nutrition, including PEG [29] . Another important fact is the change in official recommendations for HPN over the last years, repositioning HPN as a palliative treatment in cancer patients because of the relatively small proportion of PNassociated comorbidity risk factors [14,30] . Regarding the indications for HPN, we found that SBS is the most frequent indication (37%), consistent with other published data [31,32] .…”