Pp225-Mon 1,25 (Oh)2-Vitamin D3 Enhances the Stimulating Effect of Leucine and Insulin on Protein Synthesis Rate in C2c12 Skeletal Myotubes

Salles, Jérôme; Chanet, Audrey; Giraudet, Christophe; Patrac, Véronique; Jourdan, Marion; Luiking, Y.C.; Verlaan, Sjors; Boirie‌, Yves; Walrand, Stéphane

doi:10.1016/s1744-1161(12)70564-1

Cited by 2 publications

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“…Therefore, it could be argued that multicomponent nutritional therapies are more effective. With this perspective, an important role could be played also by vitamin D (at least 800-1000 IU/day), which has been shown to synergistically potentiate the anabolic activity of leucine [19] and to decrease falls and increase muscle function, particularly when given to old adults (>65 years) presenting serum insufficiency and in association with physical activity [20,21].…”

Section: Introductionmentioning

confidence: 99%

Role of muscle-targeted nutritional therapy: new data

Cereda

Veronese

Caccialanza

2022

Current Opinion in Clinical Nutrition &Amp; Metabolic Care

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Purpose of reviewTo provide an updated overview of recent efficacy data on the use of muscle-targeted nutritional therapy, which should consider the optimization of protein and essential amino acids intakes, possibly in combination with supplementation with vitamin D (correction of deficiency/insufficiency status) and v-3 fatty acids. Recent findingsIntervention studies conducted in the last years in different healthcare settings and heterogeneous patient populations support the use of muscle-targeted oral nutritional supplementation to improve muscle mass, function and physical performance in patients with sarcopenia. Higher efficacy is likely to be achieved in combination with individually tailored resistance exercise training programs and when nutritional therapy and the provision of specific nutrients result in an adequate protein-calorie balance. However, not only a reactive but also a pro-active application of this therapy could be proposed as evidence exists on the maintenance of or improvement in the same outcome variables in patients at risk of losing skeletal muscle mass.

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Section: Introductionmentioning

confidence: 99%

Role of muscle-targeted nutritional therapy: new data

Cereda

Veronese

Caccialanza

2022

Current Opinion in Clinical Nutrition &Amp; Metabolic Care

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“…Vitamin D is responsible for calcium homeostasis and therefore has an important role in bone mineralization. It is also responsible for the increased calcium uptake in muscle cells, promoting greater availability of this mineral for muscle contraction (15) which appears to enhance insulin and leucine activity, improving protein synthesis (16).…”

Section: Composition Of Bovine Milk and Its Benefits In Physical Acti...mentioning

confidence: 99%

Avaliação do uso de leite desnatado como bebida hidratante em indivíduos fisicamente ativos desidratados após exercício em cicloergômetro e seu impacto no padrão alimentar

Pegoretti¹,

Antunes²

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Cássia Pegoretti Avaliação do uso de leite desnatado como bebida hidratante em indivíduos fisicamente ativos desidratados após exercício em cicloergômetro e seu impacto no padrão alimentar. Limeira 2014 viii aumento significativo do VET. Em conjunto, nossos resultados, apontam que o consumo somente de AM pareceu ser melhor que o consumo de LD, seja ele através de três, duas ou uma dose, para repor os líquidos perdidos durante exercício em cicloergômetro.

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Pp225-Mon 1,25 (Oh)2-Vitamin D3 Enhances the Stimulating Effect of Leucine and Insulin on Protein Synthesis Rate in C2c12 Skeletal Myotubes

Cited by 2 publications

References 0 publications

Role of muscle-targeted nutritional therapy: new data

Role of muscle-targeted nutritional therapy: new data

Avaliação do uso de leite desnatado como bebida hidratante em indivíduos fisicamente ativos desidratados após exercício em cicloergômetro e seu impacto no padrão alimentar

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