2020
DOI: 10.1016/j.ejca.2020.02.011
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Practical clinical guidelines of the EOTTD for treatment and referral of gestational trophoblastic disease

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Cited by 79 publications
(105 citation statements)
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“…Treatment of hydatidiform mole consists of uterine evacuation by suction and curettage. US control isrecommended to ensure a thorough evacuation and to minimize the risk of uterine perforation (48). When gestational age is higher than 16 weeks and the uterus is particularly enlarged, the procedure carries a significant risk of bleeding and embolization of molar tissue to the lungs but the treatment must always be done (3).…”
Section: Hydatidiform Molementioning
confidence: 99%
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“…Treatment of hydatidiform mole consists of uterine evacuation by suction and curettage. US control isrecommended to ensure a thorough evacuation and to minimize the risk of uterine perforation (48). When gestational age is higher than 16 weeks and the uterus is particularly enlarged, the procedure carries a significant risk of bleeding and embolization of molar tissue to the lungs but the treatment must always be done (3).…”
Section: Hydatidiform Molementioning
confidence: 99%
“…When gestational age is higher than 16 weeks and the uterus is particularly enlarged, the procedure carries a significant risk of bleeding and embolization of molar tissue to the lungs but the treatment must always be done (3). Ergometrine or other sustained uterotonic must be started at the onset of suction curettage and continued postoperatively to enhance uterine contractility (48). In women with no childbearing desire, hysterectomy is a valid alternative to uterine curettage, but it requires careful hCG surveillance because these women could still develop GTN (49).…”
Section: Hydatidiform Molementioning
confidence: 99%
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“…Gestational trophoblastic neoplasia is a rare disease and is difficult to treat. 73 However, by knocking down Malat1 and inhibiting miR-218 in JEG-3 and JAR cells, Shi et al proved that Malat1 might be able to regulate the expression of Fbxw8 protein, an oncogene, and therefore promote cell growth. 54 In addition, certain studies have identified correlations between Malat1 expression and the onset and development of precancerous cervical lesions, 74 and vulvar squamous cell carcinoma.…”
Section: Gestational Trophoblastic Neoplasiamentioning
confidence: 99%