1996
DOI: 10.1016/0967-0661(96)00169-4
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Practical issues in distributed parameter estimation: Gradient computation and optimal experiment design

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Cited by 30 publications
(12 citation statements)
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“…The sensitivity analysis (Point et al, 1996;Vande Wouwer et al, 2000) allows one to determine the number of elution peaks and the associated concentrations needed to identify the parameters with good accuracy. The identifiability of the kinetic, LDF and ED models are also compared.…”
Section: Sensitivity Analysismentioning
confidence: 99%
“…The sensitivity analysis (Point et al, 1996;Vande Wouwer et al, 2000) allows one to determine the number of elution peaks and the associated concentrations needed to identify the parameters with good accuracy. The identifiability of the kinetic, LDF and ED models are also compared.…”
Section: Sensitivity Analysismentioning
confidence: 99%
“…A related optimality criterion was given by Point et al (1996), who investigated maximization of the Gram determinant being a measure of the independence of the sensitivity functions evaluated at sensor locations. The authors argue that such a procedure guarantees that the parameters are identifiable and the correlation between the sensor outputs is minimized.…”
Section: Optimal Sensor Location For Parameter Identificationmentioning
confidence: 99%
“…These are linearly dependent if and only if the Gram determinant gz; r vanishes, i.e., [8] The main goal of this study is to determine the experimental conditions that lead to the linear independence of all the sensitivity functions and to ensure that the sensors are located in the spatial region where the sensitivity takes the largest absolute values.…”
Section: Optimum Sensor Locationsmentioning
confidence: 99%
“…In addition to this, the sensitivity functions can provide relevant information for determining optimum experimental conditions such as those reported by Point et al [8]. The following normalized sensitivity functions were adopted:…”
Section: Sensitivity Studiesmentioning
confidence: 99%
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