Practical points in the application of oxygen transport principles

Abstract

Application of the principles of oxygen transport in the management of critically ill patients can influence the frequency of organ failure and outcome. Adequate tissue oxygen consumption in these patients may depend on a supranormal level of oxygen delivery. The equations used for calculating oxygen delivery and consumption are provided, and it is noted that clinicians should have a clear understanding of the limitations of each of the measurements included in the equations. The methods used to perform the measurements are reviewed. Widespread acceptance and use of oxygen transport protocols in treatment is only possible if the measurements on which they are based are accurate and properly interpreted.

Beyond the lung: oxygen delivery and tissue oxygenation

“…It is important to note that pulmonary oxygen consumption is not included. With the use of a pulmonary artery catheter, oxygen consumption can be measured easily and repeatedly, although it must be remembered that there are multiple potential inaccuracies in the system [6]. Total body oxygen consumption can be measured using breath-bybreath analysis of the respiratory gases.…”