To survive in the competitive environment, most organizations have adopted componentbased software development strategies in the rapid technology advancement era and the proper utilization of cloud-based services. To facilitate the continuous configuration, reduce complexity, and faster system delivery for higher user satisfaction in dynamic scenarios. In cloud services, customers select services from web applications dynamically. Healthcare body sensors are commonly used for diagnosis and monitoring patients continuously for their emergency treatment. The healthcare devices are connected with mobile or laptop etc. on cloud environment with network and frequently change applications. Thus, organizations rely on regression testing during changes and implementation to validate the quality and reliability of the system after the alteration. However, for a large application with limited resources and frequently change component management activities in the cloud computing environment, component-based system verification is difficult and challenging due to irrelevant and redundant test cases and faults. In this study, proposed a test case selection and prioritization framework using a design pattern to increase the faults detection rate. First, we select test cases on frequently accessed components using observer patterns and, secondly, prioritize test cases on adopting some strategies. The proposed framework was validated by an experiment and compared with other techniques (previous faults based and random priority). Hence, experimental results show that the proposed framework successfully verified changes. Subsequently, the proposed framework increases the fault detection rate (i.e., more than 90%) than previous faults based and random priority (i.e., more than 80% respectively).