In multiple ways, Year 2011 marked an important transition for FPGA high-level synthesis (HLS), as it went from prototyping to deployment. A decade later, in this paper, we assess the progress of the deployment of HLS technology and highlight the successes in several application domains, including deep learning, video transcoding, graph processing, and genome sequencing. We also discuss the challenges faced by today’s HLS technology and the opportunities for further research and development, especially in the areas of achieving high clock frequency, coping with complex pragmas and system integration, legacy code transformation, building on open-source HLS infrastructures, supporting domain-specific languages, and standardization. We hope that this paper can inspire more research on FPGA HLS and bring it to a new height.