Precision of High Definition Spectral-Domain Optical Coherence Tomography for Measuring Central Corneal Thickness

Abstract

Cirrus HD-OCT provides repeatable CCT measurements, good agreement between two independently trained examiners, and its systematic bias compared to ultrasonic pachymetry is clinically negligible. Therefore, research laboratories and eye clinics using Cirrus HD-OCT as a diagnostic imaging method, can also benefit from a reliable noncontact pachymeter when counseling patients with glaucoma and those undergoing corneal and refractive surgeries.

Intra and inter‐user reliability of central corneal thickness measurements obtained in healthy feline eyes using a portable spectral‐domain optical coherence tomography device

“…As a 9.4 μm discrepancy represents a 1.5% change in CCT, this difference is considered to be clinically negligible. The interoperator reliability in this study was similar to that found in human studies …”

“…As a result, SD‐OCT has become pervasive in both clinical ophthalmology and basic research. It is used extensively to evaluate the anterior segment of both normal and diseased human eyes . Although this new technology has gained popularity in the field of veterinary ophthalmology, publications documenting its use are limited and normative data, specifically of the anterior segment, are lacking …”

Spectral domain optical coherence tomography in patients after successful management of postoperative endophthalmitis following cataract surgery by pars plana vitrectomy

“…The higher acquisition speed of spectral domain OCT (SD-OCT) minimizes motion artefacts and allows a higher resolution of retinal structures [9], thus providing more extensive morphological details [10]. In recent studies, SD-OCT technology was shown to have a high accuracy and reproducibility in the imaging of retinal structures, retinal nerve fiber layer (RNFL), choroidal and corneal thickness measurements [11-15]. Many authors using enhanced depth imaging (EDI)-OCT reported satisfactory examination options and measurements of choroidal pathologies which promise choroidal OCT imaging to become a standard diagnostic procedure [5,16].…”

A spectral‐domain optical coherence tomography device provides reliable corneal pachymetry measurements in canine eyes

“…As a result of these technological advancements, SD-OCT has become popular within physician-based ophthalmology and is currently used extensively to evaluate the anterior segment (ie, cornea and anterior chamber) of human eyes (Francoz and others 2011, Konstantopoulos and others 2011, Correa-Perez and others 2012, Hong and others 2012, Soliman and others 2013). Spectral-domain OCT can achieve axial resolutions as low as 2 μm, which is substantially lower than more traditional imaging modalities used to evaluate the anterior segment (Gabriele and others 2011).…”