Preconcentration and separation of haloacetic acids by ion chromatography

Sarzanini, Corrado; Bruzzoniti, Maria Concetta; Mentasti, Edoar̈do

doi:10.1016/s0021-9673(99)00199-5

Cited by 58 publications

(39 citation statements)

References 11 publications

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“…DCA and TCA have pK a s of approximately 1.5 and 0.5, respectively (Urbansky, 2000;Jia et al, 2003;Sarzanini et al, 1999;Qu and Mou, 1999). As a result, the two haloacetic acids are found predominantly in their anionic form in solution.…”

Section: Gas Chromatographymentioning

confidence: 99%

“…IC is used more frequently with ionic analytes, and conductivity detectors are most commonly used with this type of chromatography. Sarzanini et al (1999) developed and compared IC methods for the determination HAA5 in drinking water. The two types of retention mechanisms tested were ion-interaction and anion-exchange chromatography.…”

Section: Ion Chromatographymentioning

confidence: 99%

“…Generally speaking, ECD and MS are preferred over UV detection for the detection of TCE and its metabolites, due to their ability to achieve lower LODs. One CE-UV method (Kim et al, 2001) and one IC-UV method (Sarzanini et al, 1999) for the analysis of HAAs are discussed in this paper. CE methods in general have high LODs compared to other sample separation techniques.…”

Section: Ultraviolet Detectionmentioning

confidence: 99%

“…As a result, no methods for the extraction of TCE by SPE were found. Several methods do exist, however, for the analysis of HAAs in water (Benanou et al, 1998;Martínez et al, 1998aMartínez et al, ,b, 1999Loos and Barcelo, 2001;Carrero and Rusling, 1999;Sarzanini et al, 1999) and urine (Kuklenyik et al, 2002;Calafat et al, 2003) using SPE.…”

Section: Solid-phase Extractionmentioning

confidence: 99%

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A review of analytical methods for the determination of trichloroethylene and its major metabolites chloral hydrate, trichloroacetic acid and dichloroacetic acid

Delinsky

Bruckner

Bartlett

2005

Biomedical Chromatography

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Trichloroethylene (TCE) and some of its metabolites are potentially carcinogenic compounds that the general population is commonly exposed to in drinking water. Concentrations of TCE, dichloroacetic acid (DCA) and trichloroacetic acid (TCA) given to laboratory animals in cancer bioassays are high, whereas drinking water levels of the compounds are very low. It is not clear whether the trace amounts of TCE, DCA and TCA in drinking water pose a cancer risk to humans. The accuracy of pharmacokinetic studies relies on the analytical method from which blood and tissue concentration data are obtained. Models that extrapolate cancer risks of TCE and its metabolites from laboratory animals to humans, in turn, rely on the results of pharmacokinetic studies. Therefore, it is essential to have reliable analytical methods for the analysis of TCE and its metabolites. This paper reviews the methods currently in the literature for the analysis of TCE, DCA, TCA and, to a lesser extent, chloral hydrate (CH). Additional aspects of analytical methods such as method validation, species preservation and future directions in the analysis of TCE and its metabolites are also discussed.

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Section: Gas Chromatographymentioning

confidence: 99%

Section: Ion Chromatographymentioning

confidence: 99%

Section: Ultraviolet Detectionmentioning

confidence: 99%

Section: Solid-phase Extractionmentioning

confidence: 99%

See 2 more Smart Citations

A review of analytical methods for the determination of trichloroethylene and its major metabolites chloral hydrate, trichloroacetic acid and dichloroacetic acid

Delinsky

Bruckner

Bartlett

2005

Biomedical Chromatography

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“…[15] In 1999, a closed-loop stripping analysis (CLSA) technique was employed for the determination of halogenated DBPs using GC-ECD analysis, but only results for DCAA and DBAA were reported. [16] The determination of HAAs without derivatization was possible with ion chromatography [17][18] or capillary zone electrophoresis. [19] These methods are able to achieve low detection limits, but still with a significant consumption of time and labor.…”

Section: Introductionmentioning

confidence: 99%

Analysis of haloacetic acids in water and air (aerosols) from indoor swimming pools using HS-SPME/GC/ECD

Sá

Boaventura

Pereira

2012

Journal of Environmental Science and Health, Part A

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A solid phase microextraction method was used for the analysis of nine haloacetic acids (HAAs) in water and air (aerosols) from indoor swimming pools (ISPs). The analysis is characterized by derivatization of HAAs to their methyl-esters with dimethyl sulphate, headspace solid phase microextraction (HS-SPME) with a Carboxen-polydimethylsiloxane (CAR-PDMS) fiber and gas chromatography -electron capture detector (GC/ECD). High correlation coefficients were obtained for esters mixture calibration lines and detection limits were found to be at the low ppb level. Repeatability was assessed and coefficients of variation varied from 10 to 20%. Reproducibility was also evaluated and coefficients of variation from 15 to 25% were obtained. Analytical results from four Portuguese ISPs showed that the mean concentration of total HAAs (THAAs) in water ranged from 10 ± 2 to 183 ± 28 µg/L in which 55 ± 20% corresponded to trichloroacetic and dichloroacetic acids (TCAA and DCAA). THAAs highest concentrations were directly related to higher ISPs' water organic matter content. In the lack of European specific regulation for water from ISPs and taking into consideration that ingestion is a form of exposure, THAAs concentration values were compared with drinking water maximum contamination level (MCL) of 60 µg/L proposed by the US EPA for the sum of five HAAs. In 35% of water sampling campaigns the sum of MBAA (monobromoacetic acid), MCAA (monochloroacetic acid), DCAA and TCAA exceeded that MCL value. The concentrations obtained for THAAs in the ISPs' atmosphere ranged from 5 ± 1 to 64 ± 10 µg/m 3 (T = 28 • C at 5 cm above the water surface) and were proportional to the aerosols' quantity, which was deeply related to indoor air ventilation system.

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Literature

2004

Handbook of Ion Chromatography

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Preconcentration and separation of haloacetic acids by ion chromatography

Cited by 58 publications

References 11 publications

A review of analytical methods for the determination of trichloroethylene and its major metabolites chloral hydrate, trichloroacetic acid and dichloroacetic acid

A review of analytical methods for the determination of trichloroethylene and its major metabolites chloral hydrate, trichloroacetic acid and dichloroacetic acid

Analysis of haloacetic acids in water and air (aerosols) from indoor swimming pools using HS-SPME/GC/ECD

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