Prediabetes in Young Adults and Its Association With Cardiovascular Health Metrics in the Progression to Diabetes

Suzuki, Yuta; Kaneko, Hidehiro; Okada, Akira; Matsuoka, Satoshi; Itoh, Hidetaka; Fujiu, Katsuhito; Michihata, Nobuaki; Jo, Taisuke; Takeda, Norifumi; Morita, Hiroyuki; Yamaguchi, Satoko; Node, Koichi; Yamauchi, Toshimasa; Yasunaga, Hideo; Komuro, Issei

doi:10.1210/clinem/dgac247

Cited by 6 publications

(3 citation statements)

References 29 publications

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“…Among 18 908 Japanese participants with prediabetes in an observational cohort study of claims data, nonideal BMI, BP, and TC and the number of nonideal CVH metrics were associated with an increased risk of developing diabetes. 25…”

Section: Diabetesmentioning

confidence: 99%

2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Martin,

Aday,

Almarzooq

et al. 2024

Circulation

458

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BACKGROUND: The American Heart Association (AHA), in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, nutrition, sleep, and obesity) and health factors (cholesterol, blood pressure, glucose control, and metabolic syndrome) that contribute to cardiovascular health. The AHA Heart Disease and Stroke Statistical Update presents the latest data on a range of major clinical heart and circulatory disease conditions (including stroke, brain health, complications of pregnancy, kidney disease, congenital heart disease, rhythm disorders, sudden cardiac arrest, subclinical atherosclerosis, coronary heart disease, cardiomyopathy, heart failure, valvular disease, venous thromboembolism, and peripheral artery disease) and the associated outcomes (including quality of care, procedures, and economic costs). METHODS: The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing. The 2024 AHA Statistical Update is the product of a full year’s worth of effort in 2023 by dedicated volunteer clinicians and scientists, committed government professionals, and AHA staff members. The AHA strives to further understand and help heal health problems inflicted by structural racism, a public health crisis that can significantly damage physical and mental health and perpetuate disparities in access to health care, education, income, housing, and several other factors vital to healthy lives. This year’s edition includes additional global data, as well as data on the monitoring and benefits of cardiovascular health in the population, with an enhanced focus on health equity across several key domains. RESULTS: Each of the chapters in the Statistical Update focuses on a different topic related to heart disease and stroke statistics. CONCLUSIONS: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.

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Section: Diabetesmentioning

confidence: 99%

2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Martin,

Aday,

Almarzooq

et al. 2024

Circulation

458

View full text Add to dashboard Cite

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“…Many studies have shown that ideal CVH is not only associated with a lower incidence of cardiovascular morbidity, and all‐cause mortality, 1 but also indicates a lower risk of cancer, diabetes, nonalcoholic fatty liver disease, and other diseases 3–6 . Maybe the health behaviors and factors affect the occurrence and development of these diseases by regulating the functions of multiple systems.…”

Section: Introductionmentioning

confidence: 99%

“…nonalcoholic fatty liver disease, and other diseases. [3][4][5][6] Maybe the health behaviors and factors affect the occurrence and development of these diseases by regulating the functions of multiple systems.…”

mentioning

confidence: 99%

Association of life's essential 8 and risk of fragility fractures: A large cohort study

Hou,

Zhang,

Chen

et al. 2023

Journal Orthopaedic Research

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Cardiovascular health (CVH) score is not only associated with cardiovascular diseases, but also some disorders in other systems. This study aims to investigate the association between CVH score and the risk of fragility fractures. The analysis enrolled 89,464 participants at baseline in Kailuan study initiated in 2006‐2007. All participants were then followed up every 2 years and the incidence of fragility fractures was recorded annually. A total CVH score was classified as low (0‐49 points), moderate (50‐79 points) and ideal (80‐100 points). The primary outcome was incident fragility fractures before December 31, 2021. Kaplan‐Meier was used to estimate cumulative incidence. Multivariable adjusted Cox proportional hazards regression models and time‐dependent Cox hazards regression models were used to estimate fragility fracture hazard ratios (aHR) and 95% confidence intervals (95%CI). After 13.98±2.84 years of follow‐up, a total of 1,534 cases of fragility fractures were identified, with an incidence density of 1.23 per 1000 person‐years. Compared with the low CVH group, the risk of fragility fractures was significantly lower in moderate (aHR=0.78, 95%CI:0.66‐0.92) and ideal CVH groups (aHR=0.65, 95%CI:0.51‐0.83), particularly in the age <60 group (aHR=0.72, 95%CI:0.59‐0.88; aHR=0.55, 95%CI:0.41‐0.73, respectively). Time‐dependent Cox hazards regression models, sensitivity analysis and death competition model confirmed the reliability of these findings. The ideal CVH score is associated with a decreased risk of fragility fractures. With the increase of CVH score, the risk of fragility fracture decreases.This article is protected by copyright. All rights reserved.

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Childhood maltreatment and the risk of impaired glucose metabolism or type 2 diabetes in young adults: Findings from the Lifelines Cohort Study

Deschênes,

Nearchou,

McInerney

et al. 2024

J Health Psychol

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We examined the associations between childhood maltreatment and the risk of impaired glucose metabolism (IGM) or type 2 diabetes (T2D) in young adults aged 18–35. Participants ( N = 8506) from the Lifelines Cohort Study without IGM or diabetes at baseline (2007–2013) were included. Childhood maltreatment was assessed by the Childhood Trauma Questionnaire (CTQ) and incident IGM/T2D was assessed by haemoglobin A1c levels (≥5.7%) in 2014–2017. There were 223 (2.6%) cases of IGM/T2D during the follow-up period. After adjusting for sociodemographic and health/lifestyle covariates and follow-up time, only the CTQ Sexual Abuse subscale was significantly associated with IGM/T2D (RR = 1.05 [95% CI = 1.01, 1.10]). The association remained when additionally accounting for depressive and anxiety symptoms (RR = 1.05 [95% CI = 1.00, 1.09]). Childhood sexual abuse was associated with an increased risk of IGM/T2D in young adults, highlighting the long-term metabolic consequences of childhood maltreatment.

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Prediabetes in Young Adults and Its Association With Cardiovascular Health Metrics in the Progression to Diabetes

Cited by 6 publications

References 29 publications

2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Association of life's essential 8 and risk of fragility fractures: A large cohort study

Childhood maltreatment and the risk of impaired glucose metabolism or type 2 diabetes in young adults: Findings from the Lifelines Cohort Study

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