Predicting recurrence of depression using lifelog data: an explanatory feasibility study with a panel VAR approach

Kumagai, Narimasa; Tajika, Aran; Hasegawa, Akio; Kawanishi, Nao; Horikoshi, Masaru; Shimodera, Shinji; Kurata, Kenichi; Chino, Bun; Furukawa, Toshi A

doi:10.1186/s12888-019-2382-2

Cited by 13 publications

(8 citation statements)

References 32 publications

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“…Four of these studies reported on prodromes of relapse or recurrence in patients whose MDD was judged to be in remission [16, 25, 27, 28]. In 1 study [16], during a 6-month period following discontinuation of antidepressant drugs, 4 out of 15 patients with a first MDE relapsed and required further treatment with antidepressants.…”

Section: Resultsmentioning

confidence: 99%

Prodromal Symptoms in Depression: A Systematic Review

Benasi

Fava

Guidi

2021

Psychother Psychosom

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Introduction: Appraisal of prodromal symptoms of unipolar depression may complement the traditional cross-sectional approach and provide a longitudinal perspective, according to a staging model of the illness. Objective: To provide an updated systematic review of clinical studies concerned with prodromal symptoms of unipolar depression, according to PRISMA guidelines. Methods: Keyword searches were conducted in PubMed, Scopus, and Web of Science. Longitudinal studies on prodromal symptoms and signs in adult patients primarily diagnosed with unipolar depression were selected. Findings were examined separately according to study design (i.e., retrospective or prospective). Results: Twenty-five studies met the criteria for inclusion in this systematic review. Findings indicate that a distinct prodromal symptomatology – commonly characterized by anxiety, tension, irritability, and somatic complaints – exists before the onset of unipolar depression. The duration of the prodromal phase was highly variable across studies, ranging from less than a month to several years. Prodromal symptoms profile and duration were consistent within individuals across depressive episodes. There was a close relationship between prodromal and residual symptoms of the same depressive episode. Conclusions: The present systematic review addresses an important, and yet relatively neglected, clinical issue that deserves further investigation and may be of immediate practical value. The findings provide challenging insights into the pathogenesis and course of unipolar depression, which may result in more timely and effective treatment of recurrences. The definition of a prodromal phase in depression would benefit from the joint use of symptom identification, biomarkers, and neuroimaging.

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Section: Resultsmentioning

confidence: 99%

Prodromal Symptoms in Depression: A Systematic Review

Benasi

Fava

Guidi

2021

Psychother Psychosom

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“…More research is needed here that also picks up recent findings regarding the interplay between these factors. For example, Kumagai et al ( 72 ) showed that long sleep time was an important risk factor for the recurrence of depression. However, with the current data, it was not possible singling out specific sleeping times.…”

Section: Discussionmentioning

confidence: 99%

The Impact of COVID-19 on Informal Caregiving and Care Receiving Across Europe During the First Phase of the Pandemic

Bergmann

Wagner

2021

Front. Public Health

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Purpose: We analyzed the effects of COVID-19 as well as its accompanying epidemiological control measures on health-related outcomes (physical and mental health) and unmet care needs of both caregivers and care recipients across Europe and Israel by taking into account country differences.Methods: We applied comparisons of adjusted predictions, controlling for a large set of relevant respondent characteristics, to investigate changes in the physical and mental health of caregivers and care recipients due to COVID-19. Furthermore, multilevel regression models were used to analyze the effect of individual and contextual indicators on the probability of reporting difficulties in receiving care. For the analyses, we used data from 26 countries with 51,983 respondents over 50 years based on the eighth wave of the Survey of Health, Aging and Retirement in Europe (SHARE), which had to be suspended in March 2020, and the SHARE Corona Survey fielded from June to August 2020.Results: During the first phase of the pandemic in spring/summer 2020, the frequency of providing personal care to parents increased in almost all European countries, while care to children, in turn, decreased. Parental caregivers who increased the frequency of providing personal care reported significantly more mental health strains, that is, feeling sad/depressed and anxious/nervous more often since the outbreak of the pandemic. With respect to receiving care, about one out of five care recipients had difficulty in obtaining adequate care from outside the household during the pandemic. The perception of unmet care needs was significantly associated with country differences regarding the duration of the stay-at-home orders. In contrast, the number of confirmed deaths did not have a significant effect on perceiving difficulties related to receiving care.Conclusions: Our findings show the extent of the burden to which caregivers and care recipients were exposed with respect to the unintended consequences of COVID-19-related epidemiological control measures. There is a great need within this population for interventions, which effectively reduce the burden as well as the symptoms of anxiety or depression for caregivers as well as care recipients. This should be recognized by (health) policymakers and social organizations.

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“…One could argue that the rate of depression in this population might simply demonstrate a brief, transient stage during this period of instability. However, even after treatment, the risk of relapse for depression is high, with research suggesting a 10-80% rate of recurrent episodes (dependent on depression severity) ( Holma et al, 2008 ; Kessler and Bromet, 2013 ; Kumagai et al, 2019 ; Köhler et al, 2015 ; Limosin et al, 2004 ). Therefore, identifying the risk factors for depression within this population may not only alleviate suffering during equivalent periods of precariousness, but further improve the chance of mental stability in later life.…”

Section: Discussionmentioning

confidence: 99%

Depression during the COVID-19 pandemic amongst residents of homeless shelters in France

Scarlett¹,

Davisse‐Paturet²,

Longchamps³

et al. 2021

Journal of Affective Disorders Reports

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Background Accumulating evidence suggests that the COVID-19 pandemic has negatively affected global mental health and well-being. However, the impact amongst homeless persons has not been fully evaluated. The ECHO study reports factors associated with depression amongst the homeless population living in shelters in France during the Spring of 2020. Methods Interview data were collected from 527 participants living in temporary and/or emergency accommodation following France's first lockdown (02/05/20 – 07/06/20), in the metropolitan regions of Paris (74%), Lyon (19%) and Strasbourg (7%). Interviews were conducted in French, English, or with interpreters (33% of participants, ∼20 languages). Presence of depression was ascertained using the Patient Health Questionnaire (PHQ-9). Results Amongst ECHO study participants, 30% had symptoms of moderate to severe depression (PHQ-9≥ 10). Multivariate analysis revealed depression to be associated with being female (aOR: 2.15; CI: 1.26-3.69), single (aOR: 1.60; CI: 1.01-2.52), chronically ill (aOR: 2.32; CI: 1.43: 3.78), facing food insecurity (aOR: 2.12; CI: 1.40-3.22) and participants’ region of origin. Persons born African and Eastern Mediterranean regions showed higher levels of depression (30-33% of participants) than those migrating from other European countries (14%). Reduced rates of depression were observed amongst participants aged 30-49 (aOR: 0.60; CI: 0.38-0.95) and over 50 (aOR: 0.28; CI: 0.13-0.64), compared to 18-29-year-olds. Limitations These data are cross-sectional, only providing information on a given moment in time. Conclusions Our results indicate high levels of depression among homeless persons during the COVID-19 pandemic. Predicted future instability and economic repercussions could particularly impact the mental health of this vulnerable group.

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Predicting recurrence of depression using lifelog data: an explanatory feasibility study with a panel VAR approach

Cited by 13 publications

References 32 publications

Prodromal Symptoms in Depression: A Systematic Review

Prodromal Symptoms in Depression: A Systematic Review

The Impact of COVID-19 on Informal Caregiving and Care Receiving Across Europe During the First Phase of the Pandemic

Depression during the COVID-19 pandemic amongst residents of homeless shelters in France

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