Predicting value of neutrophil–lymphocyte ratio and CURB-65 score for early clinical stability of adult community-acquired pneumonia

Ju, Xuegui; Tao, Shaoqiang; Zhou, Hui; Zeng, Qianglin

doi:10.1177/2058739219835106

Cited by 2 publications

(2 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Studies have shown that neutrophil-lymphocyte ratio, lymphocyte-monocyte ratio and platelet-lymphocyte ratio can also help to predict outcome in CAP. 23,24 But in our study no such consistent findings were observed. Though total leucocyte count and neutrophils were significantly raised in those with unfavorable outcome, their ratio was not statistically significant in our study, probably due to the proportionate rise of both the parameters.…”

Section: Resultscontrasting

confidence: 73%

Clinical and Blood Parameters in Relation to the Outcomes of Community Acquired Pneumonia

Wagley¹,

Adhikari²,

Bhattarai³

et al. 2022

JCMC

View full text Add to dashboard Cite

Background: Risk stratification of Community acquired pneumonia (CAP) is challenging for physicians. Though various biomarkers are available, they are costly or not readily available in all health care settings. This study aimed to analyze the prognostic value of routinely available clinical and blood parameters in relation to the outcome of patients admitted with community acquired pneumonia. Methods: This was a hospital-based observational study of the patients admitted to Chitwan Medical College (CMC), Nepal between August 2021 and December 2021. We enrolled patients 18 years old and above with the diagnosis of CAP in the study and excluded patients with COVID and active pulmonary tuberculosis. The outcomes of the patients were recorded as improved, not-improved, or dead. Fischer exact, Kruskal-Wallis or Mann-Whitney tests were used for analysis wherever appropriate. Results: Total 92 patients with mean age 58.2 years were enrolled in the study. Patients who were not improved or were dead had higher age (p=0.029), respiratory rate (p<0.001), shock index (p=0.013), total leukocyte count (TLC) (p=0.019), urea (p=0.046), creatinine (p<0.01), potassium (p<0.001), bilirubin (p=0.029), and lactate (P<0.05) and lower SpO2 (p<0.01), SpO2/FiO2 (p=0.018), pH (p=0.0497), and PaCO2 (p<0.001). Patients with nervous (p<0.001), cardiovascular (p=0.032) and renal system (p=0.019) involvement were also found to be associated with poor outcome. Conclusions: CAP patients with higher TLC, urea, creatinine, bilirubin and lactate, with lower SpO2, SpO2/FiO2, pH and PaCO2 and with involvement of more than one organ systems were found to have unfavorable prognosis. Higher potassium level was also found to be a potential marker of CAP severity.

show abstract

Section: Resultscontrasting

confidence: 73%

Clinical and Blood Parameters in Relation to the Outcomes of Community Acquired Pneumonia

Wagley¹,

Adhikari²,

Bhattarai³

et al. 2022

JCMC

View full text Add to dashboard Cite

show abstract

“…15 Pada populasi dewasa, skor CURB-65 dan NLR berkaitan dengan resiko instabilitas klinis setelah 72 jam pasca inisiasi terapi. 16 Kombinasi CURB-65*NLR (cut off 9,06) merupakan prediktor paling signifikan dalam menentukan resiko mortalitas pada geriatric dengan pneumonia. 17 Pada pasien kami, menilik dari skor CURB-65 dan NLR yang tinggi (prediktor instabilitas klinis awal dan resiko kematian tinggi) sehingga perawatan pasien dilakukan ICU dan tidak di rawat bangsal biasa.…”

Section: Diskusiunclassified

Pengenalan Awal Pneumonia Komunitas Resiko Tinggi yang Berkembang menjadi Sepsis pada Pasien Geratri Renta: Sebuah Laporan Kasus

Aini,

Rakasiwi,

Riyatno

et al. 2024

BIKKM

View full text Add to dashboard Cite

Sepsis adalah disfungsi organ yang mengancam jiwa yang disebabkan oleh respon tubuh yang tidak teratur terhadap infeksi. Sepsis dapat terjadi akibat infeksi yang didapat komunitas atau layanan kesehatan ,dengan pneumonia terhitung lebih dari 50% kejadian sepsis pada pasien dirawat di unit perawatan intensif rumah sakit. Angka mortalitas sepsis pada geriatri dengan community-acquired pneumonia (CAP) berada antara 14% dan 26%. Pasien wanita usia 82 tahun dibawa ke IGD karena sesak napas yang memberat 1 hari sebelumnya. Pasien didiagnosis community-acquired pneumonia dengan komorbid dan status fungsional rendah yang berkembang menjadi sepsis. Pasien dirawat di unit perawatan intensif dengan memberptimbangkan skor CURB-65, PSI dan NLR. dan mendapatkan terapi cairan dan monitor balans, double antibiotic dan penanganan multidisiplin dari dokter anestesi, dokter neurologi dan dokter jantung. Setelah mendapatkan penangan optimal dan intensif, pasien meninggal pada hari ke-7 perawatan. Pneumonia dan sepsis pada pasien geriatri merupakan tantangan tersendiri yang membutuhkan pendekatan diagnosis dan resusitasi yang tepat dan cepat. Target penanganan sepsis sesegera mungkin adalah menurunkan angka mortalitas dan morbiditas pasien. Kata Kunci: Pneunomonia Komunitas, Geriatri, Renta, Sepsis

show abstract

Predicting value of neutrophil–lymphocyte ratio and CURB-65 score for early clinical stability of adult community-acquired pneumonia

Cited by 2 publications

References 9 publications

Clinical and Blood Parameters in Relation to the Outcomes of Community Acquired Pneumonia

Clinical and Blood Parameters in Relation to the Outcomes of Community Acquired Pneumonia

Pengenalan Awal Pneumonia Komunitas Resiko Tinggi yang Berkembang menjadi Sepsis pada Pasien Geratri Renta: Sebuah Laporan Kasus

Contact Info

Product

Resources

About