2018
DOI: 10.1002/lary.27267
|View full text |Cite
|
Sign up to set email alerts
|

Prediction models for postoperative uncontrolled chronic rhinosinusitis in daily practice

Abstract: Objectives/Hypothesis The European Position Paper on Rhinosinusitis and Nasal Polyps proposes an assessment of clinical control of chronic rhinosinusitis (CRS). However, there are limited data about the percentage of postoperative control, and no prediction models for uncontrolled CRS have been reported. The aim of the study was to develop prediction models for postoperative uncontrolled CRS. Study Design Retrospective case series. Methods Patients (n = 136) who had undergone endoscopic sinus surgery at least … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

4
62
1
1

Year Published

2019
2019
2024
2024

Publication Types

Select...
8

Relationship

3
5

Authors

Journals

citations
Cited by 41 publications
(68 citation statements)
references
References 23 publications
4
62
1
1
Order By: Relevance
“…Nevertheless, only 2 biological parameters were included in the prediction model, in contrast to 5 clinical parameters, reflecting a relatively limited contribution of biological parameters to our current model. Consistent with previous findings, we found that higher CT scores, AR comorbidity, and prior surgery history were associated with poor outcome of CRS 3,5. In our study, asthma was not associated with difficult-to-treat CRS independently.…”
supporting
confidence: 92%
See 1 more Smart Citation
“…Nevertheless, only 2 biological parameters were included in the prediction model, in contrast to 5 clinical parameters, reflecting a relatively limited contribution of biological parameters to our current model. Consistent with previous findings, we found that higher CT scores, AR comorbidity, and prior surgery history were associated with poor outcome of CRS 3,5. In our study, asthma was not associated with difficult-to-treat CRS independently.…”
supporting
confidence: 92%
“…Several variables, including asthma, aspirin intolerance, previous surgery, preoperative endoscopic score, percentage of eosinophils in nasal tissue and blood, and IgE levels, have been reported to correlate with unsatisfying control of CRS. [2][3][4][5] However, current evidence is limited given to the small sample size and retrospective study design of most of the studies, and the contradictory results generated. [2][3][4][5] According to the European Position Paper on Rhinosinusitis and Nasal Polyps 2012 (EPOS 2012), 1 patients who do not achieve an acceptable level of disease control despite adequate surgery, intranasal corticosteroid treatment, and up to 2 short courses of antibiotics or systemic corticosteroids in the last year are considered to have difficult-to-treat CRS.…”
Section: A Panel Of Clinical and Biological Markers Predict Difficultmentioning
confidence: 99%
“…Current treatment modalities for nasal polyps include comprehensive medical therapy and endoscopic sinus surgery, and the primary goal of treatment is to achieve and maintain clinical control 7 . However, studies reported that over 30% of patients with nasal polyps remain uncontrolled despite current standard-of-care treatment 8, 9. Emerging evidence has suggested that this might be caused by an underlying variation of endotypes resulting in a discrepancy of clinical phenotype and disease prognosis 10, 11, 12.…”
Section: Introductionmentioning
confidence: 99%
“…Partly controlled patients experience less than two of the following items: persistent nasal blockage, mucopurulent rhinorrhoea/ postnasal drip, facial pain, impaired smell, sleep disturbance/ fatigue, diseased mucosa, and the need of a course of antibiotics or systemic corticosteroids in the last three months. Uncontrolled CRS is defined as having three or more features of partly controlled CRS and need of long-term antibiotics or systemic corticosteroids in the last month (Table E1) (1,4) . Patients who did not reach an acceptable level of control (controlled or partially controlled) despite adequate surgery, intranasal corticosteroid treatment, and up to 2 short courses of antibiotics or systemic corticosteroids in the last year were considered to have difficultto-treat CRS (1,9) .…”
Section: Baseline Assessment and Sample Collection Before Surgerymentioning
confidence: 99%
“…Numerous attempts have focused on identifying the risk factors associated with CRS poor outcome. Clinical factors, such as allergic rhinitis, asthma, high blood eosinophil ratio and high preoperative computed tomography (CT) scores were reported to be associated with an increased risk of recurrence or refractoriness in CRS (4,5) . Tissue-derived biomarkers, such as tissue eosinophilia, interleukin (IL)-5, IL-25, immunoglobulin (Ig)E and Charcot-Leyden crystals, were also assigned to predict CRS outcomes (6)(7)(8) .…”
Section: Introductionmentioning
confidence: 99%