Prediction of early mortality following hip fracture surgery in frail elderly: The Almelo Hip Fracture Score (AHFS)

Accuracy of the Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity score and the Nottingham risk score in hip fracture patients in Sweden — A prospective observational study

“…Our result of an area under the ROC curve of 0.67 is within the range of 0.64‐0.77 reported in previous studies12, 19, 21, 23, 32 and suggests an equally poor discrimination for POSSUM and the NHFS in our cohort. Interestingly, while some studies have demonstrated superior discrimination by scores specifically designed for hip fracture patients12 compared to that of general surgical risk scores several other studies have not been able to demonstrate such a difference 19, 32.…”

“…It is somewhat simpler than the POSSUM and P‐POSSUM scores and does not require insertion of operative data, and is thus more suited to preoperative risk evaluation. External validation has to our knowledge only been performed in United Kingdom and in the Netherlands 12, 21, 22, 23. A recent comparison between the POSSUM and the NHFS suggested that discrimination by the NHFS was superior to that of the POSSUM score 12.…”

Financial impact and effect on the outcome of preoperative tests for at‐risk older hip fracture patients

“…The patients who underwent non‐routine preoperative tests had significant findings in age, ASA score, days‐to‐surgery, head CT, carotid US, echocardiography, hospitalization time, mortality and postoperative procedures, compared with the patients who did not undergo them. The average 30‐day mortality was 4.9%, which is considered a reasonably fair result relative to the values reported in the literature, given an average of 1.93 days‐to‐surgery . A decreased hospitalization time was noticed for the mortality variant for the arthroplasty group.…”

“…The aging population that comprises the majority of patients who require hip surgery is characterized by multiple medical comorbidities that require meticulous evaluation before the administration of anesthesia and the performance of such major surgery. Although the preoperative preparation requires various tests to be carried out in order to minimize morbidity, as well as to anticipate medical complications for the greater safety of surgical procedures, delayed time‐to‐surgery might have adverse effects on 30‐day and 1‐year mortality . More than 97% of our cohort study group was classified as having ASA scores between 2 and 4, thus forming a high‐risk patient group of which 40% required non‐routine pre‐ and postoperative testing.…”

The Role of Dot1l in Prenatal and Postnatal Murine Chondrocytes and Trabecular Bone

“…Similarly, osteoporosis affects 5.1% of men and 24% of women over age 65 in the United States and is an important public health issue in the elderly . Resulting fractures, in particular hip fractures, can be devastating with up to 13% mortality in the first 30 days after surgery and up to 33% mortality within the first year after surgery . Although bisphosphonates, teriparatide, and denosumab are effective treatments, these medications do carry risks including osteonecrosis, atypical fractures, and in the case of denosumab, increased infection…”