Prediction of Hypertension Improvement After Stenting of Renal Artery Stenosis: Comparative Accuracy of Translesional Pressure Gradients, Intravascular Ultrasound, and Angiography

Prognostic value of renal fractional flow reserve in blood pressure response after renal artery stenting (PREFER study)

“…Thus, the evaluation of its potential prognostic value in hypertension response after renal revascularization was urgently required. Previously published studies with rFFR or hyperemic systolic translesional gradient used only offi ce BP measurements as the study endpoint [20,21]. Since they have obvious limitations, trials with 24-h ABPM were expected.…”

Clinical Outcome of Renal Artery Stenting for Hypertension and Chronic Kidney Disease up to 12 Months in the J-RAS Study

“…These studies, however, used small samples and had inconclusive results. [21][22][23] Further studies are needed to invesdid not obtain clear benefit from the procedure, that is, the "non-responders". A total of 56% of the HTN patients were considered to be responders and 44% were non-responders.…”

Controversies in the management of the renal artery stenosis

“…Evaluations for hemodynamically significant lesions in patients with renal stenosis may help improve proper patient selection for the angioplasty and stenting. In a recent study Lessar et al [31] the role of renal translesional pressure gradient and intravascular ultrasound in predicting the improvement in hypertension following renal artery stenting in patients with RAS was evaluated. In this study 62 patients had translesional pressure gradient, resting and hyperemic systolic gradient (HSG), fractional flow reserve, and mean gradient measured by a guidewire and angiographic parameters including minimum lumen area and diameter, area stenosis, and diameter stenosis measured quantitatively by intravascular ultrasound.…”