Forensic odontology has contributed significantly in forensic investigations and involves various branches of dentistry including orthodontics. The current communication presents evidence-based perspective highlighting synergistic union of different specialties for Forensic Facial Approximation (FFA). It brings forth commonality in principles of anthropology, forensic science, anthropometry, anatomy, paleontology, forensic odontology, with orthodontics, used in FFA. Various attributes and skills of orthodontists’ aid in dental and skull profiling and the corresponding sex, age, and ethnicity-based soft tissue assessments for facial soft tissue thickness (FSTT), may aid a life-like appearance. They can assist hard tissue profiling by their expertise in growth of skeletal and soft tissue, along with the evolutionary trends in occlusion, and diet formulations. Their knowledge in identifying teeth patterns, dental/skeletal jaw relationships, cranial/facial indices, vertical/horizontal facial proportions, can help prepare skull for orientation and reconstruction. The dental, photographic, and radiographic records maintained by orthodontists and general dentists are instrumental in data retrieval, used in various software, clinical, or research areas. These can provide normative values for comparative analysis or facial recreation. The orthodontists can also assist anthropologists and forensic specialists in the virtual reconstructions due to their ease in using latest digital technologies including three-dimensional (3D) facial scan, stereo-photogrammetry, 3D printing, automated soft-tissue landmarks, growth, and age predictions. Thus, the current study established the commonality in concepts of various forensic disciplines with orthodontics, which can strengthen both forensic on-field facial approximations and hard/soft tissue research to further enhance the accuracy of contemporary digital software used in FFA.