In computer chip manufacturing, the study of etch patterns on silicon wafers, or metrology, occurs on the nano-scale and is therefore subject to large variation from small, yet significant, perturbations in the manufacturing environment. An enormous amount of information can be gathered from a single etch process, a sequence of actions taken to produce an etched wafer from a blank piece of silicon. Each final wafer, however, is costly to take measurements from, which limits the number of examples available to train a predictive model. Part of the significance of this work is the success we saw from the models despite the limited number of examples. In order to accommodate the high dimensional process signatures, we isolated important sensor variables and applied domain-specific summarization on the data using multiple feature engineering techniques. We used a neural network architecture consisting of the summarized inputs, a single hidden layer of 4032 units, and an output layer of one unit. Two different models were learned, corresponding to the metrology measurements in the dataset, Recess and Remaining Mask. The outputs are related abstractly and do not form a two dimensional space, thus two separate models were learned. Our results approach the error tolerance of the microscopic imaging system. The model can make predictions for a class of etch recipes that include the correct number of etch steps and plasma reactors with the appropriate sensors, which are chambers containing an ionized gas that determine the manufacture environment. Notably, this method is not restricted to some maximum process length due to the summarization techniques used. This allows the method to be adapted to new processes that satisfy the aforementioned requirements. In order to automate semiconductor manufacturing, models like these will be needed throughout the process to evaluate production quality.The manufacture of computer chips uses a plasma reactor that contains an ionized gas to conduct a series of chemical operations on the surface of a silicon wafer. Prior to being placed in the reactor, a mask is applied to the wafer in the shape of a desired circuitry pattern. Inside the reactor, various substances are deposited on the wafer and activated away from areas that do not have the mask applied, producing trenches in the surface of the wafer. The sequence of depositions and activations is defined in a recipe, the execution of which will henceforth be referred to as a process. The success of a process is determined by measuring different aspects of the etched patterns, which is called metrology. To