The healthcare industry is ever-evolving, and advancements in this industry are happening on multiple fronts, i.e. scientific, medical, regulatory etc. This industry has witnessed significant changes concerning technology usage, which has changed the overall complexion. The advent of advanced computing tools, such as AI, ML etc., has significantly augmented the capabilities within the industry and is making this industry future ready. The healthcare industry has been reactive, i.e. it treats individuals after they get the disease; however, with the application of the latest tools, the healthcare industry is becoming more predictive, i.e. it can predict the risk profile. This is the most significant impact advanced tools have brought to this industry. Advanced computing tools are being applied to multiple functions across the industry, such as drug development, patient treatment, diagnosis, insurance reimbursement etc. As there are multitudes of applications projecting different kinds of benefits, it becomes essential that we have a tool or framework which can measure the impact. This study aimed to develop a framework to evaluate the benefits of implementing these advanced computing tools. The primary objective of this technology application should be to impact the primary outcomes, i.e. accessibility, speed and accuracy, patient compliance and affordability. We must have a framework that objectively assesses the impact and provides guidance to all the stakeholders. This paper proposes a novel 4A framework to help all stakeholders assess the effects. The central idea in healthcare is to improve a patient's life. One can do that by making medicines more productive, reducing adverse effects, improving predictability, reducing cost, improving access etc. This paper provides a strategic framework to assess the impact on the suitable parameters. Novel 4A framework measures the effect on these critical parameters, i.e. access, accuracy, affordability and adherence. As this industry touches patient's life, there are multiple concerns and the primary amongst them, especially for the technology applications, are the ones related to legal and ethical. The overall archetype proposed in this research paper takes into account and provides a framework for the impact assessment. The novel 4A framework presented in this article will serve as a tool to evaluate the impact advanced computing tools will have on the healthcare industry.