Predictive factors for spontaneous closure of atrial septal defects diagnosed in the first 3 months of life

Radzik, David; Davignon, A; Doesburg, N. Van; Fournier, Anne; Marchand, Thérèse; Ducharme, Gilles R.

doi:10.1016/0735-1097(93)90202-c

Cited by 134 publications

(108 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…2,3 Spontaneous closure of an isolated ASD has been reported in 17-84% of infants and documented at ages 2-8 years. [4][5][6] However, if the defect persists until school age, it will not close. There is no obvious advantage in delaying repair beyond the teenage years and, in fact, such delay may increase the risk of diseases, such as supraventricular tachycardia, and ventricular dysfunction.…”

Section: Discussionmentioning

confidence: 99%

Incidence and Clinical Features of Asymptomatic Atrial Septal Defect in School Children Diagnosed by Heart Disease Screening.

Matsubara

Akagi

Egami

et al. 2003

Circ J

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Incidence and Clinical Features of Asymptomatic Atrial Septal Defect in School Children Diagnosed by Heart Disease Screening.

Matsubara

Akagi

Egami

et al. 2003

Circ J

View full text Add to dashboard Cite

show abstract

“…A second mortality peak occurs in adulthood after the development of complications due to milder defects. ASDs are prevalent but a rare cause of infant death: many will close spontaneously in childhood 87 and most individuals with persisting mild defects have a normal life expectancy. 88 Earlier detection of congenital heart defects offers a survival advantage because it can avert death or prevent deterioration of clinical status before definitive surgery and thus improve outcome after operation.…”

Section: Death During the First Year Of Life From Congenital Heart Dementioning

confidence: 99%

Newborn screening for congenital heart defects: a systematic review and cost-effectiveness analysis

Knowles¹,

Griebsch²,

Dezateux

et al. 2005

Health Technol Assess

214

143

View full text Add to dashboard Cite

Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per monograph and for the rest of the world £3 per monograph.You can order HTA monographs from our Despatch Agents:-fax (with credit card or official purchase order) -post (with credit card or official purchase order or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you either to pay securely by credit card or to print out your order and then post or fax it. NHS libraries can subscribe free of charge. Public libraries can subscribe at a very reduced cost of £100 for each volume (normally comprising 30-40 titles). The commercial subscription rate is £300 per volume. Please see our website for details. Subscriptions can only be purchased for the current or forthcoming volume. Contact details are as follows: Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to Direct Mail Works Ltd and drawn on a bank with a UK address. Paying by credit cardThe following cards are accepted by phone, fax, post or via the website ordering pages: Delta, Eurocard, Mastercard, Solo, Switch and Visa. We advise against sending credit card details in a plain email. Paying by official purchase orderYou can post or fax these, but they must be from public bodies (i.e. NHS or universities) within the UK. We cannot at present accept purchase orders from commercial companies or from outside the UK. How do I get a copy of HTA on CD?Please use the form on the HTA website (www.hta.ac.uk/htacd.htm). Or contact Direct Mail Works (see contact details above) by email, post, fax or phone. HTA on CD is currently free of charge worldwide.The website also provides information about the HTA Programme and lists the membership of the various committees. HTANewborn screening for congenital heart defects: a systematic review and cost-effectiveness analysis NHS R&D HTA ProgrammeT he research findings from the NHS R&D Health Technology Assessment (HTA) Programme directly influence key decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC) who rely on HTA outputs to help raise standards of care. HTA findings also help to improve the quality of the service in the NHS indirectly in that they form a key component of the 'National Knowledge Service' that is being developed to improve the evidence of clinical practice throughout the NHS.The HTA Programme was set up in 1993. Its role is to ensure that high-quality research information on the costs, effectiveness and broader impact of health technologies is produced in the most efficient way for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined to include all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care, rather than settings of care.The HTA Programme commissions research only on topics where it has identified key gaps in the evi...

show abstract

“…ASD is one of the most common adult congenital heart defects [3,4]. It is caused by underdevelopment of the secundum septum or over-reabsorption of the primum septum.…”

Section: Discussionmentioning

confidence: 99%

Improvement in Pulmonary Function After Closure of Atrial Septal Defect in a Patient With Cystic Fibrosis

Bratincsák¹,

Rhee²,

Alstine³

et al. 2017

jshd

View full text Add to dashboard Cite

Atrial septal defect (ASD) is a major cause of left-toright intracardiac shunting. If persisting into adulthood, an ASD can lead to a larger shunt, which may eventually cause pulmonary hypertension and right ventricular failure. Large intracardiac shunts cannot be tolerated in patients with underlying lung disease such as cystic fibrosis. Although the association between an intracardiac shunt and cystic fibrosis has been reported in the literature, the impact of ASD closure on the clinical course of patients with cystic fibrosis has not been studied. Here, we report a case of ASD closure in a patient with cystic fibrosis with hypoxemia out of proportion to his lung disease. Closure of the ASD shunt resulted in significant improvement of his symptoms and pulmonary function testing.Copyright © 2017 Science International Corp. Key WordsAtrial septal defect • Septal closure device • Cystic fibrosis when significant, can cause dyspnea on exertion, which may not be well tolerated in patients with an underlying pulmonary condition such as cystic fibrosis. It is unknown whether ASD closure could lead to symptomatic improvement in these patients. Here, we report a case of ASD closure resulting in improved pulmonary function testing in a patient with cystic fibrosis with a bidirectional shunt and worsening functional capacity. Case PresentationOur patient was a 36-year-old man with cystic fibrosis diagnosed at birth with a dF508/dF508 genotype. His symptoms could be characterized as moderate airway disease complicated by chronic airway infections, pancreatic insufficiency, diabetes, and malnutrition. Progression of his clinical condition caused dyspnea with minimal exertion. He was referred to our cardiology service to be evaluated for hypoxemia out of proportion to his chronic pulmonary disease. Pulmonary function testing showed a forced expiratory volume in 1 s (FEV1) of 1.71 (43% predicted). Transesophageal echocardiography (TEE) showed a small ASD with a bidirectional shunt seen at rest (Figure 1). Right heart catheterization showed a pulmonary artery pressure of 26/7/16 mmHg and pulmonary vascular resistance of 1.7 Wood units. A decision was made to proceed with ASD closure, which

show abstract

Predictive factors for spontaneous closure of atrial septal defects diagnosed in the first 3 months of life

Cited by 134 publications

References 13 publications

Incidence and Clinical Features of Asymptomatic Atrial Septal Defect in School Children Diagnosed by Heart Disease Screening.

Incidence and Clinical Features of Asymptomatic Atrial Septal Defect in School Children Diagnosed by Heart Disease Screening.

Newborn screening for congenital heart defects: a systematic review and cost-effectiveness analysis

Improvement in Pulmonary Function After Closure of Atrial Septal Defect in a Patient With Cystic Fibrosis

Contact Info

Product

Resources

About