Predictive variables for hard cardiac events and coronary revascularization in patients with normal left ventricular myocardial perfusion and systolic function

Romero-Farina, Guillermo; Candell‐Riera, Jaume; Aguadé-Bruix, Santiago; Cuberas-Borrós, Gemma; Ferreira‐González, Ignacio; Pizzi, M.N.; León, Gustavo De; Santos, Antónia; Garcı́a-Dorado, David

doi:10.1007/s00259-013-2438-3

Cited by 6 publications

(2 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This results in the radiotracer showing equal uptake in all portions of the myocardium noted on imaging [2,7,8]. Possible mechanisms include endothelial dysfunction, the presence of collateral circulation, global transmyocardial or subendocardial ischemia, and shifts in the endocardial-epicardial flow ratio [9,10].…”

Section: Discussionmentioning

confidence: 99%

Multivessel Coronary Artery Disease Presenting as a False-Negative Nuclear Stress Test: A Case of Balanced Ischemia

Santos Argueta,

Ali,

Khan

et al. 2024

Cureus

View full text Add to dashboard Cite

Myocardial perfusion imaging (MPI) is fundamental to comparing coronary vessel perfusion levels and guides in identifying ischemic areas. However, false negatives, such as balanced ischemia, are important considerations in interpreting these results. In this case report, we describe a 77-year-old female who presented with cardiac chest pain with normal laboratory results, electrocardiogram, and imaging. However, given her history and risk factors, left heart catheterization was performed, which showed triple vessel coronary artery disease.

show abstract

Section: Discussionmentioning

confidence: 99%

Multivessel Coronary Artery Disease Presenting as a False-Negative Nuclear Stress Test: A Case of Balanced Ischemia

Santos Argueta,

Ali,

Khan

et al. 2024

Cureus

View full text Add to dashboard Cite

show abstract

“…An adverse outcome of diabetic patients with normal gated SPECT has been described 14 . In our study, DM was an independent predictor of hard events in patients with normal SPECT (1.3 vs. 0.5% per year, P < 0.001).…”

Section: Discussionmentioning

confidence: 99%

Prognostic value of stress-only and stress-rest normal gated SPECT imaging: higher incidence of cardiac hard events in diabetic patients who underwent full stress-rest imaging

Kamínek¹,

Metelková²,

Budíková³

et al. 2015

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

View full text Add to dashboard Cite

Background. The European procedural guidelines for cardiac gated SPECT imaging demonstrate considerable variability in recommended administered radiopharmaceutical activity and imaging protocols. This study compared stress-only and stress-rest protocols to evaluate the safety of stress-only imaging, and to identify characteristics of patients who need full stress-rest imaging. Methods. Patients referred for a chest pain were scheduled for stress-rest gated SPECT imaging. If the stress images were interpreted as normal according to the perfusion and left ventricular function, the examination of patients was finished and patients did not undergo the rest imaging. A total number of 1063 patients was included (mean age 61 ± 11 years). These patients have been followed for hard cardiac events, i.e. cardiac deaths or nonfatal myocardial infarction. Results. During a follow-up of 3.2 ± 2.5 years, hard events occurred in 12 patients with normal SPECT and 59 with abnormal SPECT had hard events (0.7 vs. 3.6% /year, P < 0.001). Among the 536 patients with normal study, there was no significantly lower incidence of hard events in the subgroup of patients with stress-only imaging (0.6 vs. 0.8% /year, P = 0.641). Diabetes mellitus was an independent predictor of hard events in patients with normal SPECT (1.3 vs. 0.5%/ year, P < 0.001). We found a higher incidence of hard events in diabetic patients with normal study with the necessity of full stress-rest imaging in comparison with those with stress-only imaging (1.7 vs. 0.7% /year, P < 0.001). Conclusions. Our results support the good prognosis of normal stress-only study. Diabetes mellitus was an independent predictor of hard events in patients with normal SPECT. Diabetic patients with normal results who required additional rest imaging had significant adverse outcome.

show abstract

Update on Cardiac Imaging Techniques 2013

García‐Orta

Mahia

Diego

et al. 2014

Revista Española de Cardiología (English Edition)

View full text Add to dashboard Cite

Predictive variables for hard cardiac events and coronary revascularization in patients with normal left ventricular myocardial perfusion and systolic function

Abstract: Age ≥65 years, IDDM, and LBBB are HE-independent predictors in patients with normal myocardial perfusion and normal LVEF on gated SPECT. The presence of known CAD or a positive stress test significantly increases the probability of CR during follow-up.

Cited by 6 publications

References 31 publications

Multivessel Coronary Artery Disease Presenting as a False-Negative Nuclear Stress Test: A Case of Balanced Ischemia

Multivessel Coronary Artery Disease Presenting as a False-Negative Nuclear Stress Test: A Case of Balanced Ischemia

Prognostic value of stress-only and stress-rest normal gated SPECT imaging: higher incidence of cardiac hard events in diabetic patients who underwent full stress-rest imaging

Update on Cardiac Imaging Techniques 2013

Contact Info

Product

Resources

About