Predictors and prognostic consequence of gastrointestinal bleeding in patients with ST-segment elevation myocardial infarction

Kikkert, Wouter J.; Hassell, Mariëlla E.C.J.; Delewi, Ronak; Laan, Mariet H. van der; Baan, Jan; Vis, Marije M.; Koch, Karel T.; Winter, Robbert J. de; Piek, Jan J.; Tijssen, Jan G.P.; Henriques, José P.S.

doi:10.1016/j.ijcard.2015.01.041

Cited by 18 publications

(21 citation statements)

References 30 publications

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“…With portal vein and gastric vein congestion, upper gastrointestinal bleeding appears. Three studies reported previous bleeding was positively significantly associated with GIB (Jiang et al, ; Kikkert et al, ; Ko et al, ), leading mainly to rebleeding.…”

Section: Discussionmentioning

confidence: 99%

“…As shown above, gastrointestinal diseases are associated with smoking and drinking. Chronic renal failure is one of the causes of anaemia, with findings by Girndt (2017) (Jiang et al, 2013;Kikkert et al, 2015;Ko et al, 2010), leading mainly to rebleeding.…”

Section: Disease Risk Factorsmentioning

confidence: 99%

“…Use of antithrombotic medications is necessary after PCI. As Nadatani et al (2013) showed, patients undergoing coronary artery stent FIGURE 3 Forest plots of odds ratio (OR) with 95% confidence interval (CI) for the disease risk factors of GIB after PCI in a fixed-effects model placement require long-term administration of two or more antithrombotic agents. These agents are used as adjunctive therapy to reduce the risk of ischaemic complications such as in-stent restenosis and stent thrombosis.…”

Section: Medicine-related Risk Factors and Protective Factorsmentioning

confidence: 99%

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Meta‐analysis of risk and protective factors for gastrointestinal bleeding after percutaneous coronary intervention

Wang

Ouyang

et al. 2018

Int J of Nursing Practice

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Aim To quantitatively analyse factors related to gastrointestinal bleeding after percutaneous coronary intervention and provide evidence for the prevention of gastrointestinal bleeding. Data Sources and Review Methods Cochrane Library, Pubmed, Embase, and Ovid databases were searched from inception to 31 May 2018; case‐control and cohort studies published in English were included. The methodological quality of each study was assessed by two independent reviewers using the Newcastle‐Ottawa Scale. Meta‐analysis was performed using Revman version 5.3. Results A total of 16 publications yielded data about risk factors. It was found that age older than 70 years, age (per 10‐year increase), female sex, baseline anaemia, history of smoking, history of using alcohol, history of peptic ulcer disease, chronic renal failure, previous bleeding, shock, congestive heart failure, acute myocardial infarction, prior use of inotropic medications, and prior use of antithrombotic medications were positively associated with gastrointestinal bleeding. Four articles yielded data about protective factors. It was found that proton‐pump inhibitor and bivalirudin therapy were negatively associated with gastrointestinal bleeding after percutaneous coronary intervention. Conclusion This research found risk and protective factors which can assist in effective management of this potentially fatal complication.

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Section: Discussionmentioning

confidence: 99%

Section: Disease Risk Factorsmentioning

confidence: 99%

Section: Medicine-related Risk Factors and Protective Factorsmentioning

confidence: 99%

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Meta‐analysis of risk and protective factors for gastrointestinal bleeding after percutaneous coronary intervention

Wang

Ouyang

et al. 2018

Int J of Nursing Practice

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“…Die Gabe eines Antikörpers gegen GP IIb/IIIa bei Patienten mit Myokardinfarkt erhöht ebenfalls das Blutungsrisiko [93].…”

Section: Empfehlung 24bunclassified

S2k-Leitlinie Gastrointestinale Blutung

Götz

Anders²,

Biecker³

et al. 2017

Z Gastroenterol

149

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“…Although thrombocytopenia is a rare disease in the general population, it could result in severe conditions due to extra bleeding or hemorrhage. Some of the complications might be fetal if spontaneous bleeding occurs in the gastrointestinal or intracranial [3,4].…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Thrombocytopenia and Its Association with Serum Magnesium

Zhan

et al. 2015

Biol Trace Elem Res

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The present study aimed to investigate the prevalence of thrombocytopenia and its association with serum magnesium in a nationally representative cohort. A total of 8478 participants aged 18 years and over were recruited in a cross-sectional survey. Thrombocytopenia was defined as platelet count less than 150 × 10(9)/L. Multivariable logistic regression models were applied to examine the association between serum magnesium and thrombocytopenia. The prevalence of thrombocytopenia in total was 16.5% with 18.8% for men and 14.4% for women (P < 0.0001), respectively. Compared with men in the first quartile of serum magnesium, the odds ratios (ORs) and 95% confidence intervals (CIs) for those in the second, third, and fourth quartiles of serum magnesium were 0.96 (0.75, 1.21), 0.78 (0.62, 0.98), and 0.82 (0.65, 1.04), respectively, after adjusting for multiple confounders. Likewise, the corresponding ORs (95% CIs) were 0.80 (0.63, 1.01), 0.79 (0.62, 0.99), and 0.65 (0.51, 0.84) in women. When serum magnesium was treated as a continuous variable, each one standard deviation increase of magnesium was associated with 12 and 8% lower risk of thrombocytopenia in men and women, respectively. Serum magnesium was inversely associated with thrombocytopenia, and the association was slightly different in men compared with that in women.

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Predictors and prognostic consequence of gastrointestinal bleeding in patients with ST-segment elevation myocardial infarction

Cited by 18 publications

References 30 publications

Meta‐analysis of risk and protective factors for gastrointestinal bleeding after percutaneous coronary intervention

Meta‐analysis of risk and protective factors for gastrointestinal bleeding after percutaneous coronary intervention

S2k-Leitlinie Gastrointestinale Blutung

Prevalence of Thrombocytopenia and Its Association with Serum Magnesium

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