2006
DOI: 10.1161/circulationaha.105.001354
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Predictors of Early Neurocognitive Deficits in Low-Risk Patients Undergoing On-Pump Coronary Artery Bypass Surgery

Abstract: Background-Postoperative cognitive deficits (POCDs) are a source of morbidity and occur frequently even in low-risk patients undergoing cardiac surgery.

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Cited by 50 publications
(48 citation statements)
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“…According to the results of the present study, the Syntax score seems not to be the predictor of severe cardiovascular events such as death, MI, or stroke at 1 year, thus suggesting that available cardiac operative risk evaluation scores such as the EUROSCORE should be preferred to the Syntax score to predict the outcome in patients undergoing surgery. Usual strong predictors of cardiovascular events after CABG surgery described in the literature including age, diabetes, LVEF, history of pulmonary disease, and renal failure [29][30][31][32][33][34][35] are not included in the Syntax score, which could explain the lack of prognostic value in patients undergoing CABG for 3-vessel CAD. Indeed, our results are in accordance with the fact that in multivariable logistic regression models of the seven core variables, variables relating to acuteness, age, and previous operation proved to be the most important in all data sets tested.…”
Section: Discussionmentioning
confidence: 99%
“…According to the results of the present study, the Syntax score seems not to be the predictor of severe cardiovascular events such as death, MI, or stroke at 1 year, thus suggesting that available cardiac operative risk evaluation scores such as the EUROSCORE should be preferred to the Syntax score to predict the outcome in patients undergoing surgery. Usual strong predictors of cardiovascular events after CABG surgery described in the literature including age, diabetes, LVEF, history of pulmonary disease, and renal failure [29][30][31][32][33][34][35] are not included in the Syntax score, which could explain the lack of prognostic value in patients undergoing CABG for 3-vessel CAD. Indeed, our results are in accordance with the fact that in multivariable logistic regression models of the seven core variables, variables relating to acuteness, age, and previous operation proved to be the most important in all data sets tested.…”
Section: Discussionmentioning
confidence: 99%
“…20 When elderly patients undergo CABG, however, the risk of mortality and morbidity increase with age, particularly among women, and there is a high prevalence and persistence of cognitive decline after CABG. 21,22 These factors, combined with the rapid recovery after PCI, would tend to favor PCI over CABG in elderly patients indicated for revascularization, if there were not similar age-related degradation in postprocedure outcome.…”
Section: Discussionmentioning
confidence: 99%
“…Mishra et al analysed risk factors for neurologic complications in patients with aortic atherosclerotic lesions undergoing coronary bypass surgery. The only independent factor increasing the risk of neurologic complications was CABG surgery with extracorporeal circulation (OR = 1.4) [19].…”
Section: Discussionmentioning
confidence: 99%