Predictors of health-related quality of life perceived by end-stage renal disease patients under online hemodiafiltration

Moura, Ana Rita; Madureira, José; Alija, Pablo; Fernandes, João; Oliveira, José Arimátes de; López, M.a J. Oliveras; Filgueiras, Madalena; Amado, Leonilde; Faria, Maria do Sameiro; Miranda, Vasco; Mesquita, Edgar; Santos-Silva, Alice; Costa, Elı́sio

doi:10.1007/s11136-014-0854-x

Cited by 26 publications

(17 citation statements)

References 42 publications

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“…; Moura et al . ). However, there is some controversy whether depression has a direct causal role in the poor results of treatment, or if depression is just a marker of increased associated co‐morbidities and disease severity.…”

Section: Discussionmentioning

confidence: 97%

“…Depression is a common and serious comorbid condition in patients on dialysis, with prevalence rates estimated between 20% and 44% (Kimmel & Peterson 2005;Watnick et al 2005;Hedayati et al 2006;Kimmel et al 2007). Depression has been associated with greater medical co-morbidity, lower quality of life, decreased survival and decreased adherence to dialysis prescription treatments (Cukor et al 2009;Rosenthal et al 2012;Moura et al 2014). However, there is some controversy whether depression has a direct causal role in the poor results of treatment, or if depression is just a marker of increased associated co-morbidities and disease severity.…”

Section: Gds: Geriatric Depression Scalementioning

confidence: 99%

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Self‐reported Medication Adherence in Patients With End‐stage Kidney Disease Undergoing Online‐haemodiafiltration

Amado¹,

Ferreira²,

Miranda³

et al. 2015

Journal of Renal Care

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Section: Discussionmentioning

confidence: 97%

Section: Gds: Geriatric Depression Scalementioning

confidence: 99%

Self‐reported Medication Adherence in Patients With End‐stage Kidney Disease Undergoing Online‐haemodiafiltration

Amado¹,

Ferreira²,

Miranda³

et al. 2015

Journal of Renal Care

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“…Table). For RRT treatments, KTx recipients reported higher mean generic and specific scores relative to those on dialysis [68][69][70][71][72][73][74][75][76][77][78][79][80][81][82][83] (S2-S4 Tables). Nagaraja et al [44] converted the SF-36 data into SF-6D utility scores and showed a similar relationship; kidney transplantation was associated with better mean SF-6D utility scores relative to HD (0.65± SD: 0.13 vs 0.52± SD: 0.11, respectively).…”

Section: The Kdqol-sf™ Toolmentioning

confidence: 99%

The impact of chronic kidney disease on developed countries from a health economics perspective: A systematic scoping review

et al. 2020

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Chronic kidney disease (CKD) affects over 10% of the global population and poses significant challenges for societies and health care systems worldwide. To illustrate these challenges and inform cost-effectiveness analyses, we undertook a comprehensive systematic scoping review that explored costs, health-related quality of life (HRQoL) and life expectancy (LE) amongst individuals with CKD. Costs were examined from a health system and societal perspective, and HRQoL was assessed from a societal and patient perspective. Papers published in English from 2015 onward found through a systematic search strategy formed the basis of the review. All costs were adjusted for inflation and expressed in US$ after correcting for purchasing power parity. From the health system perspective, progression from CKD stages 1-2 to CKD stages 3a-3b was associated with a 1.1-1.7 fold increase in per patient mean annual health care cost. The progression from CKD stage 3 to CKD stages 4-5 was associated with a 1.3-4.2 fold increase in costs, with the highest costs associated with end-stage renal disease at $20,110 to $100,593 per patient. Mean EuroQol-5D index scores ranged from 0.80 to 0.86 for CKD stages 1-3, and decreased to 0.73-0.79 for CKD stages 4-5. For treatment with renal replacement therapy, transplant recipients incurred lower costs and demonstrated higher HRQoL scores with longer LE compared to dialysis patients. The study has provided a comprehensive updated overview of the burden associated with different CKD stages and renal replacement therapy modalities across developed countries. These data will be useful for the assessment of new renal services/ therapies in terms of cost-effectiveness.

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“…As people with these two chronic diseases are known to have competing physical and psychological needs when compared to people with the single condition, there is a need to understand how their complex needs translate into impact on HRQoL and its specific subscales as well as the impact of increasing disease severity. Within this context there is a need for studies across the continuum from early stages of diabetes and CKD through to late stages [8] that seek to identify factors associated with HRQoL particularly those that can be modified [15]. To do this we examined factors associated with HRQoL in patients with co-morbid diabetes and CKD of varying severity who access specialist medical care from tertiary hospitals.…”

Section: Introductionmentioning

confidence: 99%

Predictors of Health-Related Quality of Life in Patients with Co-Morbid Diabetes and Chronic Kidney Disease

Zimbudzi

Ranasinha

et al. 2016

PLoS ONE

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BackgroundPeople living with diabetes and chronic kidney disease (CKD) experience compromised quality of life. Consequently, it is critical to identify and understand factors influencing their health-related quality of life (HRQoL). This study examined factors associated with HRQoL among patients with diabetes and CKD.MethodsA cross sectional study among adults with comorbid diabetes and CKD (eGFR <60 mL/min/1.73m2) recruited from renal and diabetes clinics of four large tertiary referral hospitals in Australia was performed. Each participant completed the Kidney Disease Quality of Life (KDQoL ™ -36) questionnaire, which is comprised of two composite measures of physical and mental health and 3 kidney disease specific subscales with possible scores ranging from 0 to 100 with higher values indicating better HRQoL. Demographic and clinical data were also collected. Regression analyses were performed to determine the relationship between HRQoL and potential predictor factors.ResultsA total of 308 patients were studied with a mean age of 66.9 (SD = 11.0) years and 70% were males. Mean scores for the physical composite summary, mental composite summary, symptom/problem list, effects of kidney disease and burden of kidney disease scales were 35.2, 47.0, 73.8, 72.5 and 59.8 respectively. Younger age was associated with lower scores in all subscales except for the physical composite summary. Female gender, obese or normal weight rather than overweight, and smoking were all associated with lower scores in one or more subscales. Scores were progressively lower with more advanced stage of CKD (p<0.05) in all subscales except for the mental composite summary.ConclusionIn patients with diabetes and CKD, younger age was associated with lower scores in all HRQoL subscales except the physical composite summary and female gender, obese or normal weight and more advanced stages of CKD were associated with lower scores in one or more subscales. Identifying these factors will inform the timely implementation of interventions to improve the quality of life of these patients.

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Predictors of health-related quality of life perceived by end-stage renal disease patients under online hemodiafiltration

Cited by 26 publications

References 42 publications

Self‐reported Medication Adherence in Patients With End‐stage Kidney Disease Undergoing Online‐haemodiafiltration

Self‐reported Medication Adherence in Patients With End‐stage Kidney Disease Undergoing Online‐haemodiafiltration

The impact of chronic kidney disease on developed countries from a health economics perspective: A systematic scoping review

Predictors of Health-Related Quality of Life in Patients with Co-Morbid Diabetes and Chronic Kidney Disease

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