Predictors of health‐related quality of life in patients with chronic liver disease

Afendy, Arian; Kallman, Jillian; Stepanova, Maria; Younoszai, Zahra; Aquino, Ruben D.; Bianchi, Giampaolo; Marchesini, Giulio; Younossi, Zobair M.

doi:10.1111/j.1365-2036.2009.04061.x

Cited by 146 publications

(163 citation statements)

References 22 publications

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“…Studies of other chronic diseases have reported that a variety of demographic characteristics, including sex, body mass index (BMI), severity of illness, and age, will affect HRQoL [11][12][13]. In addition, pain, age, and functional limitations have been reported to lower HRQoL in the elderly people with RA [14].…”

Section: Introductionmentioning

confidence: 99%

Association Between Rheumatoid Arthritis and Health-Related Quality of Life in Korean Women Aged 50 Years and Over

Park

2017

Asian J Pharm Clin Res

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Objective: The purpose of this study is to evaluate the association between rheumatoid arthritis (RA) and health-related quality of life (HRQoL) in Korean women.Methods: Participants (n=2068) aged 50 years or older were selected from Korea National Health and Nutrition Examination Survey (KNHANES) [2005][2006][2007][2008]. Sociodemographic characteristics, medical history of RA, and EuroQol-5 dimension were obtained from the KNHANES dataset. Results:The results revealed that demographic variables, including age, education level, income, exercise, smoking, and alcohol drinking, were important factors associated with HRQoL. In this study, RA was an important factor affecting HRQoL in Korean women. The adjusted odds ratio for HRQoL in participants with RA was 2.15 (95% confidence interval [CI]: 1.46-3.18, p=0.001) in mobility, 2.30 (95% CI: 1.60-3.32, p<0.001) in usual activities, and 3.41 (95% CI: 2.20-5.28, p<0.001) in pain/discomfort. Conclusion:These findings suggest that there is a strong association between RA and HRQoL and preventing and controlling RA may significantly improve the quality of life for elderly Korean women.

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Section: Introductionmentioning

confidence: 99%

Association Between Rheumatoid Arthritis and Health-Related Quality of Life in Korean Women Aged 50 Years and Over

Park

2017

Asian J Pharm Clin Res

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“…Os resultados encontrados neste domí-nio estão de acordo com estudos que apontam declínio da qualidade de vida nos aspectos sociais à medida que aumenta o consumo de alcoólicos 7,[36][37][38] ; da mesma forma, corroboram a afirmação da OMS de que o consumo disfuncional de alcoólicos interfere negativamente na qualidade das relações pessoais 1 .…”

Section: Consumo De Alcoólicos E Qualidade De Vidaunclassified

“…Estudos de avaliação da qualidade de vida de pacientes hepatopatas utilizando o instrumento SF-36 têm evidenciado que sua qualidade de vida relacionada à saúde se mostra diminuída em relação a controles saudáveis [6][7][8] . Comparações entre grupos com base na gravidade da doença hepática indicaram piores níveis de qualidade de vida em pacientes com cirrose 7,9 , e pesquisas de seguimento que avaliaram pacientes submetidos a transplante hepático evidenciaram posterior incremento na qualidade de vida 10,11 .…”

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“…Comparações entre grupos com base na gravidade da doença hepática indicaram piores níveis de qualidade de vida em pacientes com cirrose 7,9 , e pesquisas de seguimento que avaliaram pacientes submetidos a transplante hepático evidenciaram posterior incremento na qualidade de vida 10,11 . Poucos trabalhos avaliam o uso atual de alcoólicos em hepatopatas 7,11,12 e poucos estudos avaliaram a qualidade de vida desses pacientes utilizando o instrumento WHOQOL-Bref 13,14 .…”

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Qualidade de vida e consumo de alcoólicos em hepatopatas do sexo masculino

Martins

Ribeiro

Baracho³

et al. 2012

Rev. psiquiatr. clín.

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Resumo Contexto: O uso disfuncional de álcool é um problema com amplas consequências. Além disso, os efeitos do seu uso sobre a qualidade de vida não foram ainda muito estudados. Objetivo: Avaliar a qualidade de vida de hepatopatas e verificar suas possíveis associações com o consumo de alcoólicos e variáveis sociodemográficas. Método: Estudo transversal realizado com pacientes atendidos em ambulatório de hepatologia, entre abril e dezembro de 2009, avaliando homens entre 20 e 59 anos e escolaridade superior à 5 a série do ensino fundamental. Instrumentos: CAGE, AUDIT, WHOQOL-Bref e questionário sociodemográfico. Resultados: Pacientes CAGE positivos tiveram médias mais baixas no domínio físico do WHOQOL (p = 0,027). Aqueles que nunca usaram alcoólicos tiveram médias mais altas no domínio social comparados aos consumidores de médio e alto risco ou provável dependência no ano (p-valores, respectivamente, 0,023 e 0,036). Abstêmios e usuários de baixo risco registraram médias mais elevadas no domínio social comparados aos usuários de médio risco no último ano (p = 0,031). Conclusão: Os mais baixos níveis de qualidade de vida nos domínios físico (CAGE) e social (AUDIT) registrados pelos pacientes que informaram consumo de alcoólicos de alto risco ou provável dependência são consistentes com achados da literatura. Martins ME, et al. / Rev Psiq Clín. 2012;39(1):5-11Palavras-chave: WHOQOL-Bref, CAGE, AUDIT, uso de alcoólicos, qualidade de vida. AbstractBackground: Dysfunctional use of alcohol is a problem with broad consequences. Moreover, there exists little evidence about the impact of dysfunctional use on quality of life. Objective: To evaluate the quality of life of patients with liver diseases and to verify its possible associations with alcohol consumption and sociodemographic variables. Method: Transverse study with masculine patients between 20 and 59 years of age and with at least 5 years of primary school completed, assessed between April and December 2009 in a hepatology service. Instruments: CAGE, AUDIT, WHOQOL-Bref and sociodemographic questionnaire. Results: CAGE positive patients had a lower average in the physical domain of WHOQOL (p = 0.027). Those who never used alcohol had higher scores in the social domain compared to patients with medium and high risk consumption or probable dependence in the past year (p = 0.023 and p = 0.036 respectively). Abstainers and low-risk users recorded the highest average in the social domain compared to medium risk users in the past year (p = 0.031). Discussion: The lowest levels of quality of life in the physical (CAGE) and social (AUDIT) domains reported by patients with alcohol consumption of high risk or probable dependence are consistent with findings in the literature.

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“…Ranking within groups is presented in Table 1. 3,6,21,23,27), the activity (3 questions; the order of 7, 9, 14), emotional functioning (8 questions; the order of 10,12,15,16,19,20,24,26), as well as concerns (5 questions; the order of 18,22,25,28,29). The average score for each domain is equal to the sum of ranks for all issues related to this area, divided by the number of questions.…”

Section: Methodsmentioning

confidence: 99%

A quality of life assessment and the correlation between generic and disease-specific questionnaires scores in outpatients with chronic liver disease-pilot study

Obradović

Gluvić

Petrović

et al. 2017

Romanian Journal of Internal Medicine

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Introduction. Chronic liver diseases (CLD) are an important cause of morbidity and mortality in general population. The aim of this study was to analyze potential differences between patients with CLD and healthy control group, and to estimate the severity of CLD by using simple questionnaires: general health questionnaire (GHQ-12) and chronic liver disease questionnaire (CLDQ).Methods. A cross-sectional pilot study was performed in Zemun Clinical Hospital during years 2014 and 2015. Sixty participants were divided into 4 groups (15 per group): chronic alcoholic hepatitis, other chronic hepatitis, liver cirrhosis, and healthy control group. Entire study population chose one of four offered answers of structured questionnaires GHQ-12 and CLDQ, based on which mean model of end-stage liver disease (MELD) and Child-Turcotte-Pugh (CTP) scores were calculated.Results. Mean GHQ12 and CLDQ scores were 10.5 and 5.21 ± 1.11 respectively. Regarding certain CLDQ domain scores, a significant difference between alcoholic and non-alcoholic hepatitis groups in the worry domain was observed. Mean MELD score was 7.42 ± 2.89 and did not differ between chronic hepatitis groups, while mean CTP score was 5.73 ± 0.88. A statistically significant correlation was observed between GHQ12 and CLDQ scores (ρ = -0.404, p < 0.01), but not between subjective and objective scores.Conclusions. Mean GHQ12 and CLDQ scores pointed out to general psychological no-distress condition of the studied participants, as well as scarcely expressed CLD-specific complaints. Mean MELD and CTP scores indicated stable chronic liver diseases, with low three-month mortality rates in the cases of chronic hepatitis, as well as determination to Child A group in the case of liver cirrhosis.

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Predictors of health‐related quality of life in patients with chronic liver disease

Abstract: SUMMARY BackgroundPatient-reported outcomes like health-related quality of life (HRQL) have become increasingly important for full assessment of patients with chronic liver diseases (CLD).

Cited by 146 publications

References 22 publications

Association Between Rheumatoid Arthritis and Health-Related Quality of Life in Korean Women Aged 50 Years and Over

Association Between Rheumatoid Arthritis and Health-Related Quality of Life in Korean Women Aged 50 Years and Over

Qualidade de vida e consumo de alcoólicos em hepatopatas do sexo masculino

A quality of life assessment and the correlation between generic and disease-specific questionnaires scores in outpatients with chronic liver disease-pilot study

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